How Exosome Therapy Differ from Stem Cell Therapy
Exosomes are potent microvesicles released by adult mesenchymal stem cells. They have the ability to help restore cells in the body by improving cell to cell communication.
Exosomes are not cells, and they are smaller than cells. When compared to adult stem cells, exosomes have much more growth factors which give them a better clinical and aesthetic potential than stem cells.
It’s a cell-free cell therapy, this makes it safer compared to other cellular therapy, because there’s no risk of rejection in graft Vs host.
Unlike some other cellular therapies, exosomes do not produce host graft reactions, because they do not carry HLA genetic information and are not cells but extracts of the cells (released by cells).
Exosomes have a superior regenerative capacity, because they are obtained from newborn umbilical cord tissue mesenchymal cells, which means they have not been exposed to any contaminating or toxic agent because our cells are as healthy as our body.
Exosomes improve the signaling between cells, thereby making them useful to revitalize, rejuvenate, restore, and cause anti-inflammatory effects in the body.
When compared to autologous adult stem cells, exosomes have much more healthy growth factors which gives them a better clinical and aesthetic potential than stem cells.
Exosomes are less complicated products to transport because the cells used in cellular therapy must be applied to the patient very quickly because they are live cells. In the laboratory, once they are thawed the doctors have limited time to apply them. However, with exosomes, they last longer, because as they are proteins they do not denature and can last for longer periods.
Exosomes is a superior product to autologous treatments because they do not require a surgical procedure, they come in a vial that can be injected directly, significantly reducing the risk and complications of a surgical procedure.
It is a superior product to autologous stem cell therapy because the patient’s cells have the same age and the same quality. For example, if a patient is a smoker and intoxicated, obviously the health of his cells is not the best. That is why the most indicated product is a donor product that is pure and free of toxins.
Mesenchymal cell-derived exosomes are preferably used in regenerative medicine. These cells are excellent regenerative cells due to their multipotent nature, therefore MSCs derived exosomes are superior to other exosomes products.
The Cellgenic lyophilized exosomes are derived from mesenchymal cells, which makes it superior to other exosome products, because mesenchymal cells have superior and excellent regenerative capacity.
This is why exosome therapy, especially Cellgenic lyophilized exosomes should be a doctor’s first choice.
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Applications of Exosomes in Regenerative Medicine
In recent years, the application of exosomes in regenerative medicine has been growing. Also, many more potential applications of exosomes in regenerative medicine are still being studied.
In this article, you’ll learn the functions of exosomes and up-to-date applications of exosomes in regenerative medicine.
What are exosomes?
Exosomes are tiny vesicles that play a crucial role in cell to cell communication. Every cell in our body produces exosomes, to give information to the neighboring cells or long-distance cells, to change their behavior or to simply share information.
They transfer genetic information, proteins, and receptors, and they are capable of changing the behavior of one cell to the other. They have the ability to increase cell replication and other substances crucial for tissue regeneration.
Functions of exosomes
The major function of exosomes is to improve intercellular communication by releasing effectors and signaling molecules between cells.
Every cell in our body produces exosomes, to give information to the neighboring cells, or long distance cells, to change their behavior or to simply share information.
They transfer genetic information, proteins, and receptors, and are capable of changing the behavior of one cell to the other. They can increase cell replication and other substances crucial for tissue regeneration.
Exosomes affect all aspects of cell biology and are useful for improving intercellular communication.
Various applications of exosomes in regenerative medicine.
Exosomes have various clinical applications due to their high potency, reduced immunogenicity, and ability to cross physiological barriers such as the blood-brain barrier.
In regenerative medicine, exosomes can be used in a point of care environment for a lot of aesthetic and therapeutic purposes.
The Use of Exosomes in Hair therapy
Exosomes can be used in the early stages of hair loss to re-grow and regenerate hair.
The good thing about using exosomes for hair loss is that they can be used in both men and women.
Exosomes can help stimulate hair growth and prevent hair loss. Clinical results have also shown the efficacy of exosomes in alopecia areata.
Exosomes from follicular stem cells are said to inhibit hair loss and promote hair growth.
In the earlier stages of hair loss, hair can be regrown and regenerated in men and women by administering exosomes and growth factors.
After the first round of exosome therapy, noticeable change can be seen in 2 or 3 months but the most significant changes start from 6 to 12 months.
The Use of Exosomes in Skin-Regeneration
There are so many research and clinical trials surrounding the application of exosomes in skin treatment.
The benefits of exosome therapy in skin regeneration because of their ability to directly stimulate target cells, non-immune rejection and high stability.
These are some of the abilities of exosomes in skin regeneration:
- Regulation of inflammation
- Synthesis of collagen
- Angiogenic effect
The Anti-aging effect of exosomes
Exosomes can be used to restore aging tissues of the body due to their outstanding regenerative ability.
Signs of aging manifest due to the skin’s inability to regenerate itself, exosomes can help to maintain the skin’s elasticity and strength.
Exosome therapy is changing the approach to anti-aging treatment. The rejuvenation capability of exosomes is a great way to make your patients feel young again.
It revitalizes senescent cells by repairing damage due to aging.
With exosomes, you are improving longevity by reversing the cells that are dying due to aging.
Exosomes in Pain management
Exosome therapy can be used to relieve pain by subduing pain signals, reducing inflammation and repairing damaged tissues.
The application of Exosome in inflammatory conditions.
Exosomes can decrease inflammation, regenerate cells and modulate the immune system.
Osteoarthritis: MSC-derived exosomes can reduce the joint inflammation in osteoarthritis and also stimulates cartilage regeneration and the repair of damaged tissues.
Tendinitis: Tendinitis is the inflammation of tendons. Exosomes can reduce the inflammation associated with tendinitis and repair torn tendons and muscles.
Due to the potency of exosomes and its paracrine effect, the potential capabilities of exosomes are still being discovered and studied.
At Cellgenic, we prepare easy to transport and administer Lyophilized exosomes, suitable for use in regenerative medicine.
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ISSCA Members to Present in the XXV Congreso Internacional de Medicina, Cirugia Estética y Obesidad
The XXV Congreso Internacional de Medicina, Cirugia Estética y Obesidad will take place in CDMX, México on July 13,14 and 15, 2022. The International Society for Stem Cell Application (ISSCA) will be actively taking part in the congress. The ISSCA is a multidisciplinary community of physicians and scientists with a mission to advance the science, technology, and practice of regenerative medicine to treat diseases and lessen human suffering through science, technology, and regenerative medicine. Several ISSCA members will be presenting or giving demonstrations on the latest protocols and technologies in regenerative medicine.
- Benito Novas, the managing director of the ISSCA from the USA, will give a talk about Digital Marketing in Cash-Based Practices. Benito Novas is a global entrepreneur, manager, and keynote speaker, who specializes in marketing focused on biotechnology, life sciences, and healthcare development. He has served as the director of the ISSCA since 2016. His published books in Aesthetic Practice and Digital Marketing can be found here. In his presentation this July, he will share his visionary approach to healthcare management and regenerative medicine. Congress attendees will have the opportunity to learn why doctors must use digital marketing strategies to grow a successful practice. Benito Novas will provide tips to attendees on how to capitalize on social media trends to grow practice influence.
- Dr. Maritza Novas, the ISSCA director of education from the USA, will talk about Allogeneic Therapies and Stromal Cell Exosomes. The use of allogeneic therapy is one of the most attractive alternatives to autologous products and is of utmost interest to researchers in recent years. Exosomes serve as mediators for cell-to-cell communication and can be used as cell-free therapeutics for their special characteristics. Dr. Maritza Novas has been in aesthetic and anti-aging medicine since 2001. She is globally recognized for her work in regenerative medicine and dedicated service in education.
- Dr. Silvina Pastrana, the Argentina chapter director of the ISSCA from Argentina, will present on Fundamentals of Cellular Therapies and Mesenchymal Stem Cells (MSC). Dr. Pastrana heads a staff of medical specialists in orthopedics, rheumatology, medical clinic, and cosmetic surgery, performing procedures that incorporate stem cell therapies. She has been serving as a staff surgeon for the Hospital Dr. Prof. Luis Güemes for 21 years.
Besides the above presentations, look forward to sessions in the practical portion of the congress, where the following ISSCA members will show the latest protocols and technologies in regenerative medicine:
- Dr. Julio Ferreira (Argentina), Cosmetic Surgery / Aesthetic Medicine
- Dr. Andrea Lapeire (Argentina), Aesthetic Medicine
- Dr. Maritza Novas (USA), ISSCA Director of Education in the USA
- Dr. Silvina Pastrana (Argentina), Chapter Director of ISSCA in Argentina
The ISSCA members are the leaders in setting standards and promoting excellence in the field of regenerative medicine, related education, certification, research, and publications. The Global Stem Cells Groups (GSCG) is a group of companies, including the ISSCA and other members, dedicated to facilitating stem cell research and medicine. Making the benefits of stem cell medicine a reality for both doctors and patients worldwide is the goal of the GSCG. To learn more, visit our sites at the ISSCA and the GSCG.
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How much does exosome therapy cost?
Exosome therapy is the new buzz in the regenerative medicine industry because of how it can repair and regenerate your cells and tissues.
Exosome therapy is safer compared to other cellular therapy because it’s a cell-free therapy with no risk of rejection.
Exosome therapy will be beneficial to you if you’re dealing with conditions such as sport injuries, tissue regeneration, hair loss, erectile dysfunction, chronic pain and so many other applications .
In this article, you’ll be learning the cost of exosome therapy and how you can benefit from exosome therapy.
How the cost of exosome therapy is determined
All cells produce exosomes, which are microvesicles that contain biochemical and genetic information.
Hence, the cost of an exosome product (used in exosome therapy) will depend on what type of cell line (raw tissue source) used to extract the exosomes.
The first factor to determine the cost of an exosome product depends on the quality of the tissue source.
The most commonly used tissue types are cord blood, amniotic fluid and mesenchymal cell cultures.
Exosomes derived from mesenchymal cell cultures are the most difficult to obtain but offer the greatest therapeutic potential.
How much does exosome therapy cost?
The average cost of exosome therapy is $4,900, but the price can be anything from $3,500 – $6,500.
It’s also important to note that the price depends on your specific needs and your treatment plan, as decided by the doctor.
The doctor will schedule a consultation with you to determine your personalized treatment plan.
The exosome therapy can either be given as an IV infusion or as localized injections, depending on the purpose of the therapy.
Exosomes are very useful to revitalize, rejuvenate, restore, and reduce inflammations in the body.
Here are some ways you can benefit from exosome therapy
Hair loss therapy: If you’re in the early stages of hair loss, with exosome therapy you can regenerate your hair whether you’re a man or woman. After exosome therapy, you’ll start seeing new hair growth in as little as two to three months with very significant results showing 6 months or 1 year later.
Chronic pain: In case you’re experiencing chronic pain due to degenerative conditions such as arthritis, exosomes can help to subdue the pain by regenerating the cells and helping the body work better.
Degenerative conditions: If you’re struggling with degenerative medical conditions such as osteoarthritis and musculoskeletal injuries, exosome therapy can help your body repair the damage done to your cells by these conditions, prevent them from getting better, and help you to feel better.
Skin therapy: exosome therapy can reduce inflammation in the skin by improving the strength and elasticity of the skin.
Anti-aging: if you would like to retain your youthful glow, exosome therapy can make you feel young again by rejuvenating your skin due to its ability to reverse the cells dying due to aging.
Where can you get exosome therapy?
Cellular hope institutes provide exosome therapy for patients looking for better outcomes for various conditions.
The exosomes used at Cellular Hope Institute are obtained from umbilical cord tissue that is discarded after a new birth , which means these Exosomes have not been exposed to any contaminating or toxic agent because our cells are as healthy as our body. This gives it a higher capacity to regenerate your cells and tissues.
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Culture Expanded MSCs
Mesenchymal Stem Cells (MSCs) are the most commonly used cells in stem cell therapy and regenerative medicine, due to their high and multi-potency. Mesenchymal Stem Cells (MSCs) can be isolated from different tissues in the body.
In this article, you’ll be learning about culture-expanded MSCs, how MSCs can be expanded, The potency of MSCs and the type of cells they can differentiate into.
What are culture expanded Mesenchymal Stem cells?
Mesenchymal stem cells are high potent cells used for cellular therapy and isolated from different parts of the body. Mesenchymal stem cells can be used to improve the patient outcome in diseases and conditions such as autoimmune diseases, degenerative diseases, nerve damage, diabetes mellitus, bone problems etc.
For every patient, millions of mesenchymal stem cells are needed and the exact amount varies according to disease, route of administration, administration frequency, weight, and age of patient.
Mesenchymal stem cells are expanded in a culture media, on a large scale in order to obtain the required quantity of cells needed for cellular therapy.
Culture expanded MSCs: How does it work?
Expanding Mesenchymal stem cells in a media involves step by step process of isolation and expansion.
Mesenchymal Stem Cells Isolation
Mesenchymal stem cells can be isolated from different tissues in the human body such as adipose tissues, dental pulp, human bone marrow, umbilical cord tissue, umbilical cord blood, peripheral blood and synovium.
Mesenchymal stem cells are expanded in culture to increase their yield and amplify their desired functions and potency.
Although the population of Mesenchymal Stem Cells obtained will vary from donor to donor, here are some steps to follow:
· Acquire fresh tissue extracts in strictly aseptic conditions, to maintain purity.
· To remove any cell clusters, you have to filter the cell suspension with a 70-mm filter mesh
· Use a centrifuge to roll the cells for about 5 minutes at 500g
· Suspend the cells again the cells to measure the cell viability and yield using Trypan blue exclusion
· Use in T75 culture dishes to culture the cells in 10 mL of complete MSC medium at a density of 25 × 106 cells/mL. You can then go on to Incubate the plates at 37 °C with 5% CO2 in a humidified chamber without any interruption.
· When it’s past 3 h, remove the non-adherent cells that accumulate on the surface of the dish by changing the medium and replacing it with 10 mL fresh complete medium.
· After an additional 8 h of culture, add 10ml fresh complete medium as a replacement for the existing medium. You’ll have to repeat this step every 8 h for up to 72 h of initial culture.
· Cells can be frozen in MSC growth media plus 10% DMSO (D2650) at a density of 2X106 cells/vial.
Expansion of Mesenchymal Stem Cells in a culture media
Culture expanded mesenchymal cells undergo various stages from the preparation of the culture plate, thawing of Mesenchymal stem cells, and the actual expansion of Mesenchymal stem cells.
The reason behind the cultural expansion of Mesenchymal stem cells is to get them to differentiate into other cell types such as osteoblast, adipocyte, and mesenchymal stromal cells.
In preparation, to expand MSCs in a culture media, you need a culture ware. You can get one plastic or glassware plate and coat it with a sufficient amount of 0.1% gelatin. Don’t forget to aspirate the gelatin solution from the coated plate or flask before you use it.
The next step involves the thawing of the Mesenchymal stem cells, and here are a few steps for you to follow:
After the recommended culture medium and coated culture ware is ready and on standby, remove the vial of Mesenchymal Stem Cells from liquid nitrogen and incubate in a 37C water bath and pay close attention to it, until all the cells are completely thawed. The extent of completely thawed frozen cells and how fast, are what determines the cell viability.
Once the cells have thawed completely, take steps to avoid contamination by disinfecting the walls with 70% ethanol, before you proceed to the next step.
Place the cells in a hood, and carefully transfer the cells to a sterile tube with a pipette (1 or 2ml pipette), Do this in such a way to prevent bubbles.
Then, add drops of Mesenchymal Stem cell expansion medium that have been pre-warmed to 37C to the tube containing the Mesenchymal stem cells.
Be careful to take your time when adding the medium to avoid osmotic shock which could lead to decreased viability.
Proceed to mix the suspension slowly by pipetting up and down two times while avoiding any bubbles.
Place the tube in a centrifuge and centrifuge the tube at 300 x g for 2-3 minutes to roll the cells, and you should not vortex the cells.
After this, then decant as much of the supernatant as possible. These steps are necessary to remove residual cryopreservative (DMSO).
Suspend the cells in a total volume of 10 mL of Mesenchymal Stem Cell Expansion Medium again or any alternative of choice, pre-warmed to 37 °C, containing freshly added 8 ng/mL FGF-2 (F0291).
The next step involves placing the cell suspension onto a 10-cm tissue culture plate or a T75 tissue culture flask.
Maintain the cells in a humidified incubator at 37 °C with 5% CO2.
The next day, exchange the medium with fresh Mesenchymal Stem Cell Expansion Medium (pre-warmed to 37 °C) containing 8 ng/mL FGF-2*. Replace with fresh medium containing FGF-2 every two to three days thereafter.
Isolate the cells when they are approximately 80% confluent, using Trypsin-EDTA and passaged further or frozen for later use.
Expansion of Mesenchymal Stem Cells
Once the cells are actively proliferating and have reached a confluence of approximately 80% (before 100%), you should subculture the cells.
Then remove the medium from the 10-cm tissue culture plate containing the confluent layer of human mesenchymal stem cells, carefully and apply 3-5 mL of Trypsin-EDTA Solution, before proceeding to incubate in a 37 °C incubator for 3-5 minutes.
Crosscheck the culture to see if all the cells are completely detached. Then, add 5 mL Mesenchymal Stem Cell Expansion Medium to the plate.
Swirl the plate mildly to mix the cell suspension. Transfer the separated/isolated cells to a 15 mL conical tube.
Centrifuge the tube at 300 x g for 3-5 minutes to pellet the cells.
Throw the supernatant away and apply 2 mL Mesenchymal Stem Cell Expansion Medium (pre-warmed to 37 °C) containing 8 ng/mL FGF-2 to the conical tube and completely suspend the cells again. Remember not to vortex the cells.
Then, use a hemocytometer to count the number of cells.
Plate the cells at a density of 5,000-6,000 cells per cm2 into the appropriate flasks, plates, or wells in a Mesenchymal Stem Cell Expansion Medium containing 8 ng/mL FGF-2.
Cells can be frozen in MSC growth media plus 10% DMSO (D2650) at a density of 2X106 cells/vial.
Functions of Culture Expanded MSCs
Mesenchymal stem cells are required to be expanded in order for them to be used clinically for therapeutic purposes.
The culture expanded MSCs can be induced to differentiate into adipocytes, osteocytes, hepatocytes, chondrocytes, tenocytes and cardiomyocytes.
Because of its potential to differentiate into different kinds of cells in the body, it can be used to manage liver problems, heart problems, joint and bone problems etc.
Mesenchymal stem cells are also used in tissue regeneration and modulation of the immune system. They possess anti apoptotic, angiogenic, anti fibrotic, and anti-oxidative properties.
However, the quantity of MSCs isolated from body tissues is not enough for clinical and therapeutic applications.
This is why MSCs are expanded in culture to increase their yield for desired therapeutic effect.
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Why cellular therapies have become a standard in clinics that are betting on biological medicine
Cellular therapy is fast becoming a standard therapy in many regenerative clinics today. Many doctors are no longer questioning the safety and effectiveness of stem cell therapy. This is because various stem cell studies are already describing the benefits of stem cells for patients who are living with chronic and autoimmune health conditions.
This article will be talking about why stem cell therapy have become a standard therapy in clinics, the paracrine effect of stem cells, and other reasons why doctors are adopting stem cells in their clinics.
Benefits of stem cell therapy
Stem cell therapy is an important innovation in medicine because of its regenerative power in the human body. Most disease states are characterized by damaged cells, tissues and organs, which is where stem cell therapy comes in. In stem cell therapy, stem cells are administered into the human body and it replaces the cells damaged by disease or health disorders.
Stem cell research has revealed two major ways of using stem cells to rebuild defective and damaged cells. One of these ways can be seen in procedures like bone marrow transplant, where stem cells are used to replace the damaged cells by engraving, and they then differentiate into the proper cell type. Another mechanism relies on the paracrine effect of stem cells. This procedure of stem cell therapy involves using stem cells isolated from a donor to stimulate the patient’s cells to repair damaged tissues.
Additionally, unlike traditional therapy, stem cells have a wide application. Stem cell therapy is used to manage various degenerative diseases, autoimmune disorders, birth defects, and the research is still ongoing for so many other health conditions where stem cells have shown potential.
Also, there is currently a high demand for aesthetic medicine. Stem cell therapy is a proven alternative to other forms of cosmetology such as plastic surgery. Hence, dermatologists are turning to stem cell therapy to administer anti-aging procedures, skin rejuvenation, hair therapy, micro-needling etc.
The Paracrine effect of stem cells
The paracrine effect of stem cells is one of the most outstanding effects of stem cells. It involves using donor cells to stimulate endogenous repair by harnessing the regenerative power of the human body. It is a mechanism of tissue regeneration that has created new possibilities for managing various conditions using stem cell therapy.
The cells that trigger a paracrine response are; mesenchymal cells, umbilical cord blood, umbilical cord tissue, adipose (fat) tissue and blood cells from a donor’s bone marrow.
The paracrine effect occurs when the donor’s cells send the damaged or defective cells signals to induce self regeneration and repair by secreting some factors and proteins. One of the mechanism by which this paracrine effect is initiated, involves the secretion of cytokines and regulatory proteins by the damaged patient’s cells, these cytokines and proteins act as mediators to stimulate an immune response that attracts the donor cells, this causes the donor cells to release proteins and factors that stimulate the patient’s cells to promote cell proliferation, increase vascularization and blood flow to the areas that needs to heal, while reducing inflammation.
Moreover, research has shown that the paracrine effect of stem cells prevents damaged and diseased cells from dying. They are also therapeutically useful in autoimmune diseases and preventing transplant rejection due to the immune suppression effect they have.
Is stem cell therapy effective?
Doctors are always looking for ways to provide the best possible treatment to their patients, and that is why many clinics are embracing stem cell therapy as a standard, due to its many advantages.
Stem cell therapy is one of the most effective and safest therapy patients can receive, when compared to other existing treatment options. Stem cell therapy is used in promoting patient outcomes in a lot of disease conditions that were previously poorly treated by other alternatives.
Again, as new potentials and ways of applying stem cells are being discovered, doctors are beginning to maximize these benefits in their clinics. Some conditions that are currently treated by stem cells include autoimmune conditions, immunotherapy Car-T cells, chronic obstructive pulmonary disease, neurodegenerative conditions, osteoarthritis, spinal cord injury, aesthetics/anti-aging, sports medicine, autism and multiple sclerosis.
Another reason clinics are adopting stem cell therapy as a standard therapy is because it is easy to administer. A lot of machines such as GCELL which makes the harvesting and processing of stem cells easy and fast, have made the procedures easily adaptable by doctors.
Furthermore, stem cell therapy reduces the treatment and recovery time associated with surgical procedures and other treatment options. This alone is a big factor in why stem cells are becoming a standard therapy in clinics.
Therapeutic uses of stem cells vs traditional medicine
Existing stem cell research has shown how the regenerative effect of stem cells is defining the future of medicine. The major advantage of stem cell therapy over conventional medication-based therapy is its safety. Stem cell therapy is aimed at treating the cause of the disease while traditional medicine targets the symptoms.
Another problem with traditional medical therapy is that it introduces another problem while trying to solve the existing one. As a doctor, you always run the risk of causing harm with each prescription because of various adverse effects that could lead to major organ damage of the kidney, liver etc. On the other hand, patients already know this and they are actively seeking better alternatives, this is why stem cell therapy is fast becoming a standard therapy in clinics.
Moreover, doctors will always be concerned about whether their patients are taking their medications or not. The burden of drug compliance and adherence associated with traditional medical therapy is not always easy to navigate. This is why effective treatment options like stem cell therapy have become a standard therapy in clinics. It only requires the patients having a procedure that repairs and restores damaged cells and tissues in the most natural way.
If you would like to become certified in regenerative medicine using stem cells and other cellular therapy, contact us.
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Global Stem Cell Group Launches New Lyophilized Exosomes Product
Global Stem Cells Group is on the front line of advanced skin rejuvenation with a newly launched product.
MIAMI LAKES, Fla., April 4, 2022 – Global Stem Cells Group (GSCG) is proud to announce the launch of its new product with new lyophilized exosome technology. Global Stem Cells Group’s new product line includes innovative anti-aging products that can regenerate cells and tissues in the body.
The new product, known as Cellgenic Lyophilized Exosomes, is derived from human umbilical cord mesenchymal stem cells and includes potent growth factors, peptides, coenzymes, minerals, amino acids, vitamins and UV radiation reducing agents for skin revitalization.
This new cutting-edge product is formulated with powerful growth factors to help combat aging skin, environmental damage and loss of elasticity and tone. It has been clinically tested for its effectiveness. This innovative skincare solution is easy to use and does not require any special shipping or storage requirements. It can be used as an add-on treatment with any other Global Stem Cells Group cosmetic products.
The exosome technology involves the freeze-drying of extracellular vesicles (EVs). These EVs are isolated from mesenchymal stem cell cultures that have been expanded in the laboratory. The Lyophilized Exosomes are then reconstituted with saline in front of the patient just before use.
It has been shown that these vesicles contain RNA, proteins and metabolites which promote wound healing, angiogenesis, tissue regeneration and anti-inflammatory effects when applied topically to the skin.
Global Stem Cells Group is on the front line of advanced skin rejuvenation. The company’s new product, Lyophilized Exosome, can be shipped anywhere in the world without refrigeration. This technology is a first for exosome preparation and will revolutionize the way that skin care professionals do business.
With offices in multiple countries around the globe, Global Stem Cells Group has become one of the fast-growing companies in its field. Now, with the launch of a new product, Lyophilized Exosomes, they are poised to continue that growth and solidify their position as a leader in advancing regenerative medicine worldwide.
“Our goal at Global Stem Cells Group is to develop the most effective regenerative products on the market,” said Benito Novas, CEO of Global Stem Cells Group. “Our new product line of lyophilized exosomes is a testament to our commitment to developing cutting edge products with great clinical utility.”
To learn more about Cellgenic Flow Exosomes, visit https://cellgenic.com/.
About Global Stem Cells Group
Global Stem Cells Group is a worldwide network of physicians and scientists dedicated to the advancement of stem cell therapies and regenerative medicine. It has developed a comprehensive stem cell therapy protocol that includes harvesting, processing, banking, and administering adult stem cells. Global Stem Cells Group administers a constant flow of knowledge and innovation regarding the role of stem cells in modern medicine. The company’s aim is to accelerate the process of getting promising stem cell research and technology developed into treatments and therapies, and made available to physicians and patients.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
Media Contact:
Benito Novas
305-560-5337
info@stemcellsgroup.com
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ISSCA Partners With Ramzan Ali Syed Hospital to Developing and advancing cellular therapies in Pakistan
First-of-its-kind Cellular Therapy Training for doctors and medical practitioners in Pakistan
Newswise — Miami, FL –March 9th, 2022- The International Society for Stem Cell Applications (ISSCA) and Global Stem Cells Group (GSCG) today announced a new partnership with Ramzan Ali Syed Hospital (RASC) to develop autologous bone marrow stem cell and exosome-based cell therapies and advance new therapeutic options for patients in the region.
“Regenerative medicine is a fast-paced field that is growing exponentially every year as more and more research is being conducted and products are being used in clinics and doctors’ offices worldwide. -Said- Benito Novas Managing director of the International Society for Stem Cell Applications. We are very proud to be able to collaborate with our hosts in Pakistan for the development of this medical specialty”.
To stay abreast of current research, Ramzan Ali Syed Hospital partners with organizations like ISSCA and Global Stem Cells Group to provide continuing education opportunities for the doctors and specialists in Pakistan who want to learn more about how they can incorporate cellular therapies into their practice and help more patients with the latest generation of biologics and regenerative medicine products.
The first physician training course will be held in Lahore, Pakistan on March 30th – 31st & April 1st. Attendees will receive hands-on training on current protocols for MSC’s derived stem cell therapies, Exosomes, Bone Marrow derived stem cells, and PRP treatments as well as information about the most recent clinical applications with cellular medicine.
“This is the first time that ISSCA and Ramzan Ali Syed Hospital join forces for a stem cell certification course in the country, and this partnership will allow for more courses to be held in the future. This collaboration was born out of a desire to bring new technologies and cutting-edge treatments to patients throughout the country”. Said Dr. Mehmood Shaukat, Head of Pediatric Surgery
“With Pakistan’s Ramzan Ali Syed Hospital as the newest member of the ISSCA community, we look forward to strengthening our relationship with the country and offering more support within the region,” said Benito Novas, CEO of the Global Stem Cells Group and Managing Director of ISSCA USA. “We know there is a lot of potential for cell therapies to have a huge impact here. Our goal is always to help patients and doctors have access to the best possible care, no matter where they live.”
Physicians looking to offer regenerative medicine treatments can benefit from the ISSCA and Ramzan Ali Stem Cell Center trainings, which are conveniently held onsite at the Ramzan Ali Syed Hospital, To learn more about the onsite training for doctors and other opportunities offered by ISSCA, visit https://www.issca.us
About ISSCA
The International Society for Stem Cell Application (ISSCA) is a multidisciplinary community of scientists and physicians, all of whom aspire to treat diseases and lessen human suffering through advances in science, technology, and the practice of regenerative medicine. ISSCA serves its members through advancements made to the specialty of regenerative medicine.
The ISSCA’s vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, research, education, training, and certification.
As a medical specialty, regenerative medicine standards and certifications are essential, which is why ISSCA offers certification training in cities all over the world. The goal is to encourage more physicians to practice regenerative medicine and make it available to benefit patients both nationally and globally. Incorporated under the Republic of Korea as a non-profit entity, the ISSCA is focused on promoting excellence and standards in the field of regenerative medicine.
About Ramzan Ali Syed Hospital
Ramzan Ali Stem Cell Center is an all-inclusive healthcare facility in regenerative medicine located in the premises of Ramzan Ali Syed Hospital at 21 Temple Road, Lahore, Pakistan. It is a pioneering institution with a passion for the safety of all its patients. We will make sure to give you all the information you require to guide you in making better decisions for your health.
About GSCG
Global Stem Cells Group (GSCG) is a worldwide network that combines seven major medical corporations, each focused on furthering scientific and technological advancements to lead cutting-edge stem cell development, treatments, and training. The united efforts of GSCG’s affiliate companies provide medical practitioners with a one-stop hub for stem cell solutions that adhere to the highest medical standards.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
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Stem Cell Center Opens Facility in Argentina, Bringing Advanced Health Technology
December 24th, 2021: Stem Cell Center has opened a new location in Córdoba, Argentina. Looking to bring regenerative medicine technologies to Argentina, the grand opening of the center was attended by 80 attendees at the new IMEB facilities, and broadcast for viewers across Argentina and the rest of the world to stream online.
As a division of Global Stem Cells Group, Stem Cell Center is an international network of medical practices dedicated to bringing stem cell therapies to patients across the world. By uniting a group of medical practitioners in the field, they are able to provide training, equipment, and resources to practitioners who in turn offer research and knowledge to the community. As a group, they are continuously developing new treatments, making them available, and bringing the best possible care to patients in the pursuit of stem cell technology.
The launch of the new facility brings the group one step closer to their shared goal of reducing human suffering across the world, now making strides to provide access to these medical technologies in Argentina. Each new launch contributes to the acceleration of the process of developing and translating stem cell research into treatments and therapies that are accessible to both patients and physicians.
“Opening the center in Córdoba is a major step toward that goal, allowing us to give solutions to patients without drugs, instead manifesting the potential that lies within the body itself to trigger biological regeneration processes,” says Benito Novas, Founder of Global Stem Cells Group. This latest opening was made possible by a partnership and alliance between founder of Global Stem Cells Group, Benito Novas, and Director of IMEB, Doctor Luis Alejandro Mazzarini.
“This inauguration marks the launch of the pursuit of regenerative medicine, cell therapy, and tissue engineering treatments in Córdoba,” says Benito Novas. “I founded the group in 2010, as an expert in marketing, life sciences, and healthcare development. At the time, I was interested in the new progress that was being made in the field and was eager to make them available to as wide an array of patients as possible across the world.”
“We believe stem cell medicine is the future of the medical industry, and we work closely with regulators, policymakers, and medical professionals to foster this technology and harness the true potential.”
The seminal launch of this science, research and medical facility is one effort in the global mission of Stem Cell Center, who have announced a partnership with Bioscience Cell factory, offered training in Bolivia, and opened centers in Spain, Mexico, and Iraq. The global effort to reduce suffering is achieved one facility at a time, through the dedication of scientists, doctors, and researchers who believe in the untapped and often inaccessible potential of stem cell regenerative technology.
To learn more about the Stem Cell Center, visit their website here: https://stemcellcenter.net/about/
- Published in News
ISSCA organizes regenerative medicine symposium in alliance with IMEB in Córdoba, Argentina
The World Symposium on Stem Cells and Regenerative Medicine attracted a notable global audience interested in exploring the latest trends in regenerative medicine
MIAMI LAKES, Florida (December 22, 2021)—The International Society for Stem Cell Application (ISSCA), a multidisciplinary community of scientists and physicians collaborating to treat diseases and lessen human suffering through science, technology, and regenerative medicine, recently hosted a two-day symposium in Córdoba, Argentina. Held on December 10-11, 2021, the symposium featured onsite and virtual attendance options, attracting a large global swath of physicians, medical specialists, surgeons, dentists, veterinarians, and other professionals interested in regenerative medicine.
ISSCA hosted the event in conjunction with the support of the Argentine Society of Biological and Holistic Medicine (SAMByH) and the Global Stem Cells Group at the facilities of the Institute of Evolutionary and Biological Medicine (IMEB) in Río Cuarto. Eighty attendees were invited to attend the onsite symposium, while hundreds of additional attendees across the globe joined in virtually.
The symposium featured a number of notable experts across the world sharing their insight and expertise on various emerging topics and trends in regenerative medicine. Topics included general cell biology concepts, treatment of various diseases and conditions using regenerative medicine, uses of regenerative practices in aesthetic medicine, and more. Attendees were able to gain additional insight through question-and-answer panels with symposium presenters. Throughout the two-day event, attendees also enjoyed networking opportunities.
“The ISSCA is pleased to have collaborated with SAMByH and IMEB to bring the World Symposium on Stem Cells and Regenerative Medicine to the world. It was a resounding success, and we are thrilled that attendees took away valuable insight into the current state of and future projections for the world of regenerative medicine,” said Benito Novas, ISSCA Director. “Our goal is to help physicians and practitioners better treat their patients suffering from degenerative diseases by giving them the tools and education they need to implement regenerative protocols in their own practices. Our latest symposium has done just that, furthering the advancement of attendees’ knowledge and interest in the field as a viable treatment protocol for their patients.”
“We are thrilled to have collaborated with the ISSCA in bringing this symposium to life,” said Dr. Alejandro Mazzarini, Director of IMEB. “It was exciting to share our facility and the important work we’re doing at IMEB with the world and have such a high caliber of attendees join us for this important event.”
To learn more about the ISSCA’s latest news and innovations, visit https://www.issca.us/.
About ISSCA
The International Society for Stem Cell Application (ISSCA) is a multidisciplinary community of scientists and physicians, all of whom aspire to treat diseases and lessen human suffering through advances in science, technology, and the practice of regenerative medicine. ISSCA serves its members through advancements made to the specialty of regenerative medicine.
The ISSCA’s vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, research, education, training, and certification.
As a medical specialty, regenerative medicine standards and certifications are essential, which is why ISSCA offers certification training in cities all over the world. The goal is to encourage more physicians to practice regenerative medicine and make it available to benefit patients both nationally and globally. Incorporated under the Republic of Korea as a non-profit entity, the ISSCA is focused on promoting excellence and standards in the field of regenerative medicine.
- Published in News