Global Stem Cells Group Collaborates with Guadalajara Hospital Angeles del Carmen
ISSCA’s training assists hospital in developing better protocols for gynecological treatments
MIAMI LAKES, Florida—The International Society for Stem Cell Application, a multi-disciplinary community of scientists and physicians collaborating to treat diseases and lessen human suffering through science, technology, and regenerative medicine, traveled to Guadalajara, Mexico in early February to collaborate with area physicians on how to utilize advancements in stem cell research and technology to find new solutions to health issues and concerns.
During ISSCA’s visit to Hospital Angeles del Carmen, physicians with the group partnered with Dr. Norma Patricia Ramos, director of the hospital’s gynecological department. During the two-day visit, ISSCA’s researchers and physicians provided valuable training and guidance on how stem cells can be used to develop better protocols for treating vaginal stenosis.
Vaginal stenosis is a condition that causes narrowing and/or loss of flexibility of the vagina and is a side effect of radiotherapy and/or genital surgery. It is often also accompanied by dryness and loss of resiliency of scar tissue.
The group reviewed new and effective treatment protocols available through stem cell therapies, including combining traditional CO2 laser treatments with stem cells harvested from adipose tissue.
The group also worked with Dr. Ramos and her team on new stem cell protocols to help women who have tried in vitro fertilization to get pregnant but have not experienced success due to a lack of ovarian reserves. The ISSCA group shared new research on the viability of utilizing stem cells from adipose tissue or bone marrow and reintegrating it into the ovaries using a laparoscopy with the goal of increasing ovarian reserves and increasing chances of pregnancy. Poor ovarian reserve (POR) is critical limiting factor for the success of any treatment modality for infertility, and new stem cell treatments provide a promising treatment protocol in increasing the quantity and quality of oocytes in women of reproductive age.
ISSCA is committed to partnering with physicians and researchers worldwide who have a vested interest in finding new solutions to improve treatments for any conditions. The group has an upcoming trip to Buenos Aires to partner with orthopedic doctors to discuss opportunities for stem cell therapies to improve treatment protocols in the field of orthopedics.
To learn more about ISSCA, visit https://www.issca.us/.
About ISSCA:
The International Society for Stem Cells Applications (ISSCA) is a multidisciplinary community of scientists and physicians, all of whom aspire to treat diseases and lessen human suffering through advances in science, technology, and the practice of regenerative medicine. Incorporated under the Republic of Korea as a non-profit entity, the ISSCA is focused on promoting excellence and standards in the field of regenerative medicine.
ISSCA bridges the gaps between scientists and practitioners in Regenerative Medicine. Their code of ethics emphasizes principles of morals and ethical conducts.
At ISSCA, their vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, research, education, training, and certification. ISSCA serves its members through advancements made to the specialty of regenerative medicine. They aim to encourage more physicians to practice regenerative
medicine and make it available to benefit patients both nationally and globally.
For more information, please visit https://www.issca.us/ or send an email to info@stemcellsgroup.com
- Published in News
Stem Cells Offer Hope for Hair Growth
UCLA researchers have discovered a new way to activate the stem cells in the hair follicle to make hair grow. The research may lead to new drugs that could promote hair growth for people with baldness or alopecia, which is hair loss associated with such factors as hormonal imbalance, stress, aging or chemotherapy. Hair follicle stem cells are long-lived cells in the hair follicle that are present in the skin and produce hair throughout a person’s lifetime. They are quiescent, meaning they are normally inactive, but they quickly activate during a new hair cycle, which is when new hair growth occurs. The quiescence of hair follicle stem cells is regulated by many factors. In certain cases, they fail to activate, which is what causes hair loss.
The study by Heather Christofk, PhD, and William Lowry, PhD, both of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, found that hair follicle stem cell metabolism is different from other cells of the skin. Cellular metabolism involves the breakdown of the nutrients needed for cells to divide, make energy and respond to their environment. The process of metabolism uses enzymes that alter these nutrients to produce metabolites. As hair follicle stem cells consume the nutrient glucose — a form of sugar — from the bloodstream, they process the glucose to eventually produce a metabolite called pyruvate. The cells then can send pyruvate to their mitochondria — the part of the cell that creates energy — or convert pyruvate into another metabolite called lactate.
The research team first blocked the production of lactate genetically in mice and showed that this prevented hair follicle stem cell activation. Conversely, in collaboration with the Rutter lab at the University of Utah, they increased lactate production genetically in the mice, which accelerated hair follicle stem cell activation, increasing the hair cycle.
The team identified two drugs that, when applied to the skin of mice, influenced hair follicle stem cells in distinct ways to promote lactate production. The first drug, called RCGD423, activates a cellular signaling pathway called JAK-Stat, which transmits information from outside the cell to the nucleus of the cell. The research showed that JAK-Stat activation leads to the increased production of lactate, and this in turn drives hair follicle stem cell activation and quicker hair growth. The other drug, called UK5099, blocks pyruvate from entering the mitochondria, which forces the production of lactate in the hair follicle stem cells and accelerates hair growth in mice.
“Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation,” Nature Cell Biology, August 14, 2017
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ISSCA Launches New Board Aimed at Connecting Professionals in Regenerative Medicine
The society’s board helps scientists and physicians in the field make connections to improve research and provide safer and more effective patient care
MIAMI LAKES, Florida— The International Association for Stem Cell Application, a multi-disciplinary community of scientists and physicians collaborating to treat diseases and lessen human suffering through science, technology, and regenerative medicine, has announced the launch of a new online board that will help to promote the organization’s goal of facilitating the interchange of information, research, and training between physicians and scientists across the globe.
The launch of the new board comes on the heels of ISSCA’s recent announcement of a new leadership team for the society, which has recognized the importance of more easily facilitating global connections between scientists and physicians working to use stem cell research, technology, and science to better human lives.
The board, located on ISSCA’s webpage at https://www.issca.us, serves as a one-stop location for practitioners in the field of stem cell research and technology to find other practitioners across the globe and easily make connections in order to help grow their professional network, exchange best practices and research, improve standards of quality, and standardized treatment protocols in this fast-growing area of medicine that is still in its infancy.
Because regenerative medicine is a new area of medicine, physicians and scientists in the field are largely self-taught without adherence to any standards. ISSCA’s goal is to act as a resource to this burgeoning field and to help practitioners receive proper training and to standardize treatment protocols in an effort to deliver safer and more effective treatments to patients. The launch of the new board will help the society further reach this goal.
Professionals practicing regenerative medicine are encouraged to become members of the society to help assure proper training in the field and compliance with international protocols. Membership into the society will allow practitioners to be featured in the new board and have access to valuable research to standardize their knowledge, access opportunities to become certified in the field, attend professional conferences, and network with other professionals with the same interests of improving the field of regenerative medicine.
To learn more about ISSCA and the view the newly launched board, visit https://www.issca.us/
About ISSCA:
The International Society for Stem Cells Applications (ISSCA) is a multidisciplinary community of scientists and physicians, all of whom aspire to treat diseases and lessen human suffering through advances in science, technology, and the practice of regenerative medicine. Incorporated under the Republic of Korea as a non-profit entity, the ISSCA is focused on promoting excellence and standards in the field of regenerative medicine.
ISSCA bridges the gaps between scientists and practitioners in Regenerative Medicine. Their code of ethics emphasizes principles of morals and ethical conducts.
At ISSCA, their vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, research, education, training, and certification. ISSCA serves its members through advancements made to the specialty of regenerative medicine. They aim to encourage more physicians to practice regenerative
medicine and make it available to benefit patients both nationally and globally.
For more information, please visit https://www.issca.us/ or send an email to info@stemcellsgroup.com
- Published in News
ISSCA Announces Global Venues for the 6th Annual Regenerative Medicine Symposium
The Symposium will bring the latest trends, developments and commercialization opportunities from the field of regenerative medicine.
(January 9, 2019) – The International Association for Stem Cell Application (ISSCA) is pleased to announce the venues for its 6th Annual Symposium – Applications of Cell Therapies in Medicine and Aesthetic Surgery. The first symposium will be held in May in Barcelona, Spain, followed by Santiago, Chile in July, and Buenos Aires, Argentina on August 16-17, 2019. The Symposium will then proceed to the cities of Bangkok, Brussels and Miami.
The 2019 edition of ‘Applications of Cell Therapies in Medicine and Aesthetic Surgery’ in regenerative medicine promises to be as exciting as the previous edition. The event will focus on the regenerative medicine field, promising therapies for newer and wider spectrum of diseases and medical conditions and how to accommodate them.
Attendees at the 2019 ISSCA Symposium will be introduced to various aspects of stem cell and regenerative medicine solutions through rigorous scientific discussions and Q&A sessions. The topics covered will include:
- Latest trends in stem cell research
- International regulations on managing research and clinical applications
- Applications, product development and commercialization related to stem cell and regenerative medicine
- Business opportunities, marketing tools for patient recruitment, challenges and how to overcome them
This year, the Symposium will bring together students from the global medical community, renowned and well known experts and international speakers from the fields of stem cell research and regenerative medicine. Some of the organizations represented include the Global Stem Cells Group, Stem Cell Center Buenos Aires, Chilean Association of Tissue Engineering and Shockwaves ACHITOC, Investigaciones Artroscopicas SA, Argentine Arthroscopy Association, and Boston Médical Group Spain.
ISSCA’s mission is to support the paradigm shift taking place in healthcare in the 21st century, which is moving from traditional to regenerative medicine. The Symposium is part of its efforts to share and spread the most up to date information on the current advances and cutting-edge developments taking place in stem cell research and regenerative medicine.
The 2018 editions of the Symposium were held at Buenos Aires, Istanbul and Caracas, Venezuela, and were a runaway success. The Buenos Aires event was attended by over 350 physicians from around the world, and over 200 physicians attended the other two editions. The enthusiastic participation has motivated ISSCA to host the event in Buenos Aires for the next consecutive six years.
To learn more about the ISSCA Buenos Aires symposium and to reserve a seat, please visit the stemcellconference.org website, email: info@stemcellsgroup.com, or call: +1305 560 5337.
Venues for the Barcelona, Santiago and Buenos Aires 2019 ISSCA Symposium:
May 2019
Hotel W Barcelona
Plaça Rosa dels Vents, 1,
Final Passeig de Joan de Borbó
Barcelona, España 08039
July 2019
Sheraton Santiago Hotel and Convention Center
Avda. Santa María 1742
Providencia. Santiago, Chile
August 2019
Sheraton Buenos Aires Hotel and Convention Center
San Martin 1225/1275
Buenos Aires, Argentina 1104
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ISSCA Offers Cutting Edge Stem Cell and Regenerative Technologies to Clinical Practices Worldwide.
Regenerative medicine is one of the most fascinating fields in medical science. ISSCA is opening two new education centers in order to keep promoting excellence in the field of regenerative medicine.
The International Society for Stem Cells Applications (ISSCA) is set to open two Regenerative Medicine education centers in Tunisia and Belgium.
With this new development, ISSCA is significantly achieving its objective of bringing together as members and professionals of the science for productive collaborations around the Stem Cell research in all its possible fields. ISSCA has created a platform for physicians to collaborate actively, initiate discussions, share comment and exchange information that may be directly translated to therapeutic applications.
ISSCA’s Stem cells and Regenerative Medicine course provides competency training and certification to allied health professionals involved in the practice of Regenerative Medicine. The courses are designed to sequentially build a knowledge foundation to allow physicians to understand and verbalize basic and advanced scientific concepts pertaining to all aspects of Regenerative Medicine.
ISSCA believes the realm of regenerative medicine offers physicians and patients the most exciting frontier in medicine today, and they strive to make it available to them. Physicians should take ISSCA certification because it offers the advantage of world-class research with the endorsement of prestigious medical schools and clinical enterprise. ISSCA offers physicians the opportunity to learn about new, up to date technologies that are applicable to modern therapeutic approaches like stem cell applications.
As a medical specialty, regenerative medicine standards and certifications are essential; which is why ISSCA offers certification training in cities all over the world. ISSCA physicians learn the skills they need to implement regenerative medicine protocols in their practice. Once the participant completes all the units successfully, he/she receives a certificate of training.
About ISSCA:
The International Society for Stem Cells Applications (ISSCA) is a multidisciplinary community of scientists and physicians, all of whom aspire to treat diseases and lessen human suffering through advances in science, technology, and the practice of regenerative medicine. Incorporated under the Republic of Korea as a non-profit entity, the ISSCA is focused on promoting excellence and standards in the field of regenerative medicine.
ISSCA bridges the gaps between scientists and practitioners in Regenerative Medicine. Their code of ethics emphasizes principles of morals and ethical conducts.
At ISSCA, their vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, research, education, training, and certification. ISSCA serves its members through advancements made to the specialty of regenerative medicine. They aim to encourage more physicians to practice regenerative
medicine and make it available to benefit patients both nationally and globally.
For more information, please visit: https://www.issca.us/ or send an email to infor@stemcellsgroup.com
- Published in News
Which Works Better, Viscosupplementation, or Platelet Rich Plasma?
One of the treatments that the FDA approved for knee arthritis is a Hyalronic Acid (HA) injection, sometimes also known as Viscosupplementation. It has been incredibly successful for knee arthritis. In fact, so successful that many physicians are starting to use it on other parts of the body, like the hip and shoulder, which the FDA does not approve of.
HA, when injected, works like the fluid that naturally surrounds your joints. This fluid can be like a lubricant for your joints, and absorb shock, allowing bones that otherwise cause arthritis pain cause much less. Over time, it is even absorbed into the joint, which can cause the body to create a more stable cartilage all on its own.
The evidence for this treatment is astounding, with a systematic review of 76 trials, all of which were randomized controller trials. The review noted that HA, when injected, can benefit function, reduce pain, and can be a reliable and effective treatment for knee osteoarthritis.
On the other hand, there is PRP therapy. Platelet Rich Plasma, or PRP, which is a type of blood that has 6 to 10 times more platelets than what is normally found in blood. They even contain many growth factors, such as Epidermal Growth Factor, Connective Tissue Growth Factor, and many more. These can help heal injured parts of the body by using the bodies natural healing tools.
However, PRP is not regulated by the FDA, and devices that are used to make PRP require said approval. Aside from this, multiple studies shoe that PRP can be very effective in the treatment of tendon injuries, as well as for osteoarthritis. This treatment can even help in the reduction of pain. There are even more studies being conducted on whether it can help other things, such as hair regrowth, cardiac muscle repair, and even dermatologic rejuvenation.
So should you use HA injections, or PRP?
In many studies, PRP has bee demonstrated to work just as well, if not better than HA. HA is also only FDA approved for the knee, meaning that it is not approved or covered for the use in any other joint. Also, the risk of infection and rejection is far less while using PRP, as it is a substance that comes from your own body, and contains white blood cells, which can help fight infection.
PRP also saves money in the long run, as using HA in a joint other than the knee is not FDA approved or covered by insurance. As a result, it can cost your patient 1500$ or more. This can even be on top of various other charges, such as doctors visits, and even the injection itself. PRP, on the other hand, only costs from 800 to 1200$ out of pocket.
So PRP has been demonstrated to be just as effective, if not better, than HA injections when it comes to arthritis pain. It does not pose a risk for infection or and auto-immune reaction either, and is even far cheaper than HA. So picking which one to use should be a no-brainer.
- Published in Blog
How Regenerative Microneedling Can Help Rejuvenate Skin?
One of the main things that causes many people cosmetic distress and low self esteem is acne scarring. Most of us have some kind of experience when it comes down to scarring, but the most embarrassing scars are the ones that are out in the open. Such as on our faces. So what can Platelet Rich Plasma do for this?
Well, both the Department of Dermatology, Venereology, and Leprosy, as well as the National Institutes of Medical Sciences have indicated that it can be used as a viable treatment for eliminating scars. One study, done by the Department of Dermatology, Venereology, and Leprosy, sought to evaluate just how effective and safe PRP therapy can be, especially when combined with microneedling. Microneedling has been a common treatment on its own for acne scars, using distilled water, for a long time.
The way that Microneedling works is that it is used to initiate collagen synthesis on the face, thus allowing the skin to heal itself. What it does is cause micro injuries to the skin of the face using small needles. However, since the needles are so small and fine, that it does not cause any serious injury. The initiation transmits electrical signals, which calls on the body to begin a healing process, by causing small inflammation and bringing growth factors to the area.
This healing process causes new blood cells to form, and thus helps to remove the scarring over time. General treatment times are known to take from just a couple of weeks up to a year in many cases. 50 patients were involved in this study, all aged 17-32, and all suffering from acne scars.
On one side of the face, they used regular distilled water combined with the microneedling procedure, and on the right they used a topical solution of PRP. After 3 treatments giving withing the time span of a 3 months, each treatment being 1 month apart, the results that used PRP was much more likely to show improvement over the distilled water group. This would be 62.2% improvement vs 45.8% respectively. This showed that PRP can have great success in managing acne scars, and helping to make them go away.
This shows that when it comes to PRP therapy, the science again shows that there is a good and significant use for it. So what is stopping you from implementing this therapy for your patients?
- Published in Blog
ISSCA announces the 2019 Regenerative Medicine Certification Calendar
MIAMI, Dec. 4, 2018—The International Society for Stem Cell Application (ISSCA) has released its 2019 regenerative medicine certification training course calendar, with programs scheduled in seven international cities and updated curriculum. ISSCA’s objective in 2019 is to provide enhanced educational qualifications to physicians looking for a new approach to treat patients suffering with chronic pain, severe injury, and degenerative conditions and diseases.
The two-day regenerative medicine training course, which teaches easy-to-follow protocols for harvesting adipose and bone marrow stem cells from patients in a clinical environment, will also feature new treatment basics involving allogeneic compounds including exosomes and other compounds derived from (umbilical) cord blood and amniotic fluid, allowing participating physicians to easily and efficiently add certification in cutting-edge regenerative medicine therapies to their practices.
Participating physicians learn how to harvest and isolate bone marrow and adipose-derived autologous stem cells to use in treating multiple conditions.
The two-day course begins with a four-hour lecture on advances in regenerative medicine. Participating physicians will receive more than 12 hours of hands-on training with live patients in protocols for obtaining stem cells from patients, applications that they can take back to their medical offices or clinics and begin using immediately.
Attendees will also receive 12 protocols in digital format to take with them, and gain knowledge and practical skills to easily add regenerative medicine therapies to their practices.
Physicians will also receive access to the online stem cell training course to review all content and procedures introduced in the 2-day clinical training course, patient forms and guidelines, procedure informed consent forms, didactic lectures, training booklets and more.
The 2019 ISSCA training course calendar is as follows:
January 18-19, 2019 Miami, Fla. (conducted in Spanish language).
http://cursocelulasmadre.com/entrenamiento-miami-mail/ January 25.26, 2019 Miami, Fla. (Conducted in English language). https://www.stemcelltraining.net/miami-stem-cells-course-adwords/
February 1-2, 2019 Quito, Ecuador
February 8-9, 2019 Buenos Aires, Argentina
February 15-16, 2019, Lima, Peru
Fenruary 22-23, 2019 Bogota, Colombia
March 1-2, 2019 Mexico City, Mexico
https://cursocelulasmadre.com/entrenamiento-cancun-mail/ – needs to be fixed – links to a December date!
March 8-9 Abu Dabhi, UAE
https://www.stemcelltraining.net – not a good link! Please correct
ISSA’s stem cell certification course offers practical, personalized training in stem cell harvesting and isolation procedures. To date, ISSCA has trained more than 2,000 physicians worldwide.
Stem cell therapies continue to revolutionize the healthcare industry and help improve the quality of life for patients.
To learn more about the ISSCA certification training courses and to register to participate, visit the Stem Cells Training website, the email info@stemcellsgroup.com, or call 305-560-5337.
About ISSCA:
The International Society for Stem Cell Application (ISSCA) is a multidisciplinary community of scientists and physicians, all of whom aspire to treat diseases and lessen human suffering through advances in science, technology and the practice of regenerative medicine. ISSCA serves its members through advancements made to the specialty of regenerative medicine.
The ISSCA’s vision is to take a leadership position in promoting excellence and setting standards in the regenerative medicine fields of publication, research, education, training, and certification.
As a medical specialty, regenerative medicine standards and certifications are essential, which is why ISSCA offers certification training in cities all over the world. The goal is to encourage more physicians to practice regenerative medicine and make it available to benefit patients both nationally and globally. Incorporated under the Republic of Korea as a non-profit entity, the ISSCA is focused on promoting excellence and standards in the field of regenerative medicine.
- Published in News
ISSCA to Host 6th Annual Regenerative Medicine Symposium in Buenos Aires, Argentina Aug. 16-17, 2019
MIAMI, Dec. 18, 2018—The International Association for Stem Cell Application (ISSCA) has announced plans to host its sixth annual “Applications of Cell Therapies in Medicine and Aesthetic Surgery” regenerative medicine symposium in Buenos Aires, Argentina August 16-17, 2019. The focus of the symposium agenda will be allogeneic compounds—how they have changed the regenerative medicine industry, and how the industry will accommodate the challenges allogeneic therapies present.
The international symposium is part of ISSCA’s mission to support a paradigm shift in healthcare from traditional to regenerative medicine in the 21st Century and provide cutting-edge information on developments in all areas of stem cell research.
In 2018, the 5th annual symposium was held in three international cities—Buenos Aires, Istanbul, Turkey and Caracas, Venezuela. Each event exceeded organizers’ expectations both in attendance numbers and active participation. More than 200 physicians from the U.S., South America, Europe, the Middle East and Asia attended the symposiums in Istanbul and Caracas, and more than 350 physicians from around the world attended in Buenos Aires.
The high attendance and enthusiastic participation of attendees at the Argentina symposium, which was held at the Universidad de Buenos Aires, compelled ISSCA organizers to reconsider their multi-country strategy and host the event exclusively in Buenos Aires in 2019. In addition, ISSCA has committed to hosting the annual symposium in Buenos Aires for the next six consecutive years.
In keeping with ISSCA’s commitment to supporting the most current advances in stem cell and regenerative medicine discoveries, the 2019 symposium will explore the impact the acceleration of allogeneic compounds have had on the industry, new challenges they bring to the market, and promising new therapies they are expected to provide to an ever-widening spectrum of diseases and medical conditions.
A group of renowned international speakers, experts in the field of stem cell and regenerative medicine including the latest advances in allogeneic therapies, will lead rigorous scientific discussions and Q&A sessions with physicians in attendance. In Addition, ISSCA has invited representatives from [name of’ lab?], one of the world’s largest regenerative medicine labs to share their experiences and knowledge with physicians representing the global medical community in attendance,
The symposium will incorporate the biology, medicine, applications, regulations, product development, and commercialization of stem cells and regenerative medicine solutions.. In addition, business opportunities, industry challenges, and potential strategies for overcoming those challenges will be discussed.
The event venue in Buenos Aires will be announced shortly.
To learn more about the ISSCA Buenos Aires symposium and to reserve a seat, visit the stemcellconference.org website, email info@stemcellsgroup.com, or call +1305 560 5337.
- Published in News
