Global Stem Cells Group and ReGen Form Strategic Partnership to Advance Regenerative Care Worldwide
Global Stem Cells Group, a leader in the field of regenerative medicine, proudly announces an innovative partnership with ReGen, a highly acclaimed Turkish clinic renowned for its cutting-edge technologies in aesthetic and regenerative care. This strategic alliance exemplifies Global Stem Cells Group’s commitment to advancing the field of regenerative medicine and expanding global access to transformative treatments.
As a trailblazer in the industry, Global Stem Cells Group actively seeks strategic partnerships with companies and organizations that share its vision of advancing regenerative care. The collaboration with ReGen signifies a remarkable milestone in this endeavor.
A Solid Partnership
ReGen, a highly regarded clinic specializing in advanced regenerative care technologies, has joined forces with Global Stem Cells Group to facilitate the expansion of franchising opportunities for specialized regenerative care clinics worldwide. By harnessing the collective strengths of both organizations, this partnership aims to cultivate an environment where their shared expertise and services can flourish, delivering regenerative healthcare solutions to individuals across the globe.
Rapid Growth
Through the partnership, ReGen has experienced remarkable growth, leveraging the Global Stem Cells Group’s name and resources to open two state-of-the-art clinics in Buenos Aires, Argentina, and Cancun, Mexico. These clinics have established themselves as pioneers in the field of regenerative care, surpassing existing alternatives in the region.
By introducing cutting-edge aesthetic treatments such as the perfected hair transplant technique from Turkey, ReGen is revolutionizing the landscape of regenerative healthcare. The clinics now offer patients access to the latest and most effective treatment options available. ReGen’s ability to bring their expertise to new regions underscores Global Stem Cells Group’s vision of making their exceptional services accessible to individuals worldwide.
The Trained Expert Behind ReGen
Leading the way at ReGen is Dr. Salih Yildirim, an esteemed CEO with a visionary mindset committed to spearheading a paradigm shift in the realm of regenerative medicine. Driven by an unwavering passion to extend the benefits of cutting-edge aesthetic technologies hailing from Turkey, encompassing areas such as hair transplantation, rhinoplasty, mammoplasty, and stem cell treatments, he has taken the momentous decision to expand the global presence of ReGen clinics. This strategic alliance with the esteemed Global Stem Cells Group aims to grant greater accessibility to Turkey’s esteemed aesthetic and regenerative medicine treatments, catering to a broader spectrum of patients.
Evident in this initiative is ReGen’s resolute dedication to disseminate its advanced techniques and state-of-the-art technologies across the globe, thereby propelling progress in the field of regenerative medicine.
How Global Stem Cells Group Can Improve ReGen’s Reach
While ReGen brings its advanced techniques and expertise to the partnership, Global Stem Cells Group offers a range of valuable resources. As a conglomerate of companies engaged in product manufacturing and comprehensive training through the International Society for Stem Cell Application (ISSCA), Global Stem Cells Group enhances the partnership’s outreach and impact. This collaboration has the potential to be life-changing for individuals seeking regenerative care worldwide.
Dr. Yildirim expresses his satisfaction with the partnership, stating, “We are delighted to join forces with Global Stem Cells Group. This collaboration allows us to establish additional points of care globally, furthering the accessibility of stem cell applications and advancing regenerative medicine.”
This milestone partnership between Global Stem Cells Group and ReGen is destined to reshape the world of regenerative care. It represents a turning point that will be remembered as a transformative moment for the field of regenerative medicine.
Benito Novas, CEO of Global Stem Cells Group, emphasizes the significance of this alliance, stating, “Our collaboration with Dr. Yildirim spans several years, and he has consistently demonstrated exceptional leadership and humility. By incorporating the ReGen program into the Global Stem Cells Group umbrella, which encompasses products manufacturing, ISSCA training, and centers of excellence for point-of-care regenerative medicine, we continue to solidify our commitment to excellence.”
As this partnership evolves, both organizations will continue to work tirelessly to develop new treatments, enhance existing procedures, and ensure the highest standards of patient care. Through their joint efforts, they will accelerate the adoption of regenerative care practices on a global scale, creating a ripple effect that will benefit patients and healthcare providers alike.
For more information about Global Stem Cells Group and its regenerative medicine solutions, please visit https://www.stemcellsgroup.com/.
About Global Stem Cells Group
Global Stem Cells Group is a leading provider of regenerative medicine solutions, dedicated to advancing healthcare through innovative therapies. With a global presence and a multidisciplinary team of experts, the organization strives to harness the potential of stem cells and regenerative medicine to improve patient outcomes across various medical fields. Through its extensive network of clinics, research facilities, and training centers, Global Stem Cells Group is committed to pushing the boundaries of regenerative medicine and making a positive impact on global healthcare.
About ReGen
ReGen is a highly acclaimed Turkish clinic renowned for its expertise in cutting-edge technologies related to regenerative care. Headquartered in Istanbul, ReGen has gained international recognition for its commitment to excellence and its groundbreaking advancements in regenerative medicine. By partnering with Global Stem Cells Group, ReGen aims to share its advanced techniques and expertise on a global scale, improving access to regenerative care and transforming lives worldwide.
Safe Harbor Statement: Statements in this news release may be “forward-looking statements”. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions, or any other information relating to our future activities or other future events or conditions. These statements are based on current expectations, estimates, and projections about our business based partly on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties, and assumptions that are difficult to predict. Therefore, actual outcomes and results may and are likely to differ materially from what is expressed or forecasted in forward-looking statements due to numerous factors. Any forward-looking statements speak only as of the date of this news release, and The Global Stem Cells Group undertakes no obligation to update any forward-looking statement to reflect events or circumstances after the date of this news release. This press release does not constitute a public offer of any securities for sale. Any securities offered privately will not be or have not been registered under the Act and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.
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GSCG Announces the Appointment of Dr. Rafael Moguel as New Chief Medical Officer (CMO) of Cellular Hope Institute Cancun
Global Stem Cells Group (GSCG) has announced the appointment of Dr Rafael Moguel as the new Chief Medical Officer (CMO) of Cellular Hope Institute Cancun.
Dr. Moguel, Fellow of the Society for Cardiac Angiography and Intervention (SCAI), Member of the Mexican Society for Interventional Cardiologists, and Member of the Latin American Society for Interventional Cardiology, comes with a wealth of experience and training.
As CMO with vast knowledge and experience, Dr Moguel is expected to change the direction of Cellular Hope Institute Cancun, which offers patients the best treatments in multiple areas, such as sports medicine, pediatric care, chronic degenerative disease, and autoimmunity. It’s a multi-specialty training center for cellular therapies and regenerative medicine, offering the most advanced treatments in cell therapy.
“I have full confidence in the appointment of Dr Rafael Moguel as the CMO of Cellular Hope Institute Cancun,” said Benito Novas, CEO of Global Stem Cells Group. The CEO also expressed his satisfaction in Dr Moguel’s abilities and experience, and is confident that (Dr Moguel) will advance the objectives of Cellular Hope Institute and propel it to new heights.
With his impressive resume, Dr. Moguel has served in various capacities across several top medical institutions. He was the assistant professor for Cardiology and Interventional Cardiology at Hospital 1° de Octubre, where he also handled hemodynamics and internal medicine.
In his acceptance speech, Dr Moguel said, “I want to affirm and reaffirm my commitment to the goals of Cellular Hope Institute.” With his elaborate working experience and professionalism in cellular therapy, he expressed his confidence in rising to the expectations of Cellular Hope Institute.
Dr. Moguel received his medical degree at Universidad Veracruzana in 1983. He holds a valid certification by the Mexican Cardiology Board for Interventional Cardiology. With more than 10,000 interventional procedures, most notably peripheral and brain intervention, coronary, pacemakers and vein interventions, we believe Dr. Moguel has all it takes to propel Cellular Hope Institute to the next level.
The appointment of Dr. Moguel comes barely two months after an earlier announcement by GSCG about opening the multispecialty regenerative medicine center in Cancun. The facility’s main objective is to incorporate different treatments basing on regenerative medicine, and serve as a training center for cellular therapies and regenerative medicine.
We believe Dr. Moguel’s rich background as an assistant professor and head of interventional cardiology and hemodynamics positions him as the best candidate to run Cellular Hope Institute. His experience is expected to make this facility one of the best cellular therapy centers worldwide, and provide more specialized treatment for patients requiring regenerative medicine.
About Cellular Hope Institute
This facility is a center for both patients and medical experts worldwide, and its main objective is to benefit medical experts and patients globally. The facility achieves this objective through offering the best treatments for patients with multiple conditions, such as spinal cord injury, chronic obstructive pulmonary, sports medicine, and autoimmunity, among others. If you need more information about Cellular Hope Institute, please contact us today.
About the Global Stem Cell Group
Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products, and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators, and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions. With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.
Global Stem Cells Group’s corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCG’s six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
To learn more about Global Stem Cells Group, Inc.’s companies visit our website.
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Medical applications of exosomes
Medical applications of exosomes
Exosome therapy is gaining popularity in regenerative medicine. So what exactly are exosomes? Exosomes are particles that are released but cannot be replicated. They are intrical in how cells talk to each other. One cell will have a bunch of vesicles that leave and head to another cell to deliver a “message.” These vesicles contain information in the form of chemicals, cytokines to particles of messenger RNA.
Where are Exosomes found?
Exosomes are produced from stem cells and can be found in a variety of tissues.

How are they different from Stem Cells?
Exosomes are contained in stem cells. They are messenger cells that travel to communicate with other cells to produce the needed proteins to repair damaged areas. The use of exosomes does not require donor cells to be injected in the body. Exosomes can be extracted from mesenchymal stem cells (MSCs), sterilized and then injected into the body.
Stem cell therapy injects donor cells into a specific location. These stem cells grow and divide to repair the injured area and create healthier cells overtime. Exosomes are extracted from mesenchymal stem cells and like stem cells are injected into the injured area. Exosomes get to work at communicating with the patient’s own cells and enhance communication among the cells to generate the necessary and needed cells for healing.
What Exactly is Exosome Therapy ?
Exosome products are generally used for orthopedic injuries. Much like stem cell therapy, the exosomes would be injected into the injured site. This is generally an outpatient therapy that is relatively painless.
What does Exosome Therapy Treat? (Medical applications)
Exosome therapy is used for a variety of musculoskeletal injuries, chronic pain, degenerative diseases and genetic disorders. Aging and injuries suppress your cells ability to communicate with each other. The whole purpose of exosomes is to promote communication between cells to repair damaged tissues.
Exosomes are also used to help repair the skin from effects of aging. Overtime, the dermal layer of the skin is damaged because of fragmentation in the collagen, resulting in the signs of aging and hindering the ability to heal wounds. Exosomes have been found to help the body ramp up its collagen production. Exosomes also help inhibit inflammatory cytokines. This means exosomes can help with Atopic Dermatitis, a common skin disorder.
Exosomes can also help with lyme disease. Lyme disease is a very complex disease that compromises the immune system. This can lead to the disruption of cellular health and function. Oftentimes, lyme disease patients experience difficulty with inflammation which exosomes are also known to treat.
Are Exosomes Safer than Stem Cells
While both therapies have a low risk of complications, exosome therapy does not involve a surgical procedure for harvesting cells. Stem cells’ primary job is to grow and divide new and healthy cells from the donor cells. At times these cells may rapidly multiply resulting in a tumor. Exosomes do not multiply, rather they are responsible for improving the communication among cells.
If you want to become a specialist in stem cell therapies, exosomes and MSCs with us, check our next training dates here
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What is Exosome Therapy?
What is Exosome Therapy?
Some of the most cutting edge treatments in regenerative medicine today are based on exosome therapy. Studies of this cellular therapy have yielded optimistic prospects, and have shown that exosomes can be used in a wide array of applications and types of treatments.
Being such a new therapy, it is important to know their chief characteristics, how they work, and the functions that they are responsible for, as well as how these details are crucial in treatment with exosomes.
What Are Exosomes?
Exosomes are small extracellular vesicles that are secreted by cells. They are responsible for intercellular communication, where they basically act as messengers carrying valuable protein signals and genetic information (DNA & RNA) between the cells.
They can spread throughout the whole body, delivering messages that tell the cells how to behave, what is happening in the nearby area, or what they should be producing. These messengers are produced by the cells in our own body naturally, and Stem Cells are the chief producers.
What Does Treatment With Exosomes Entail?
Exosomes, being mainly produced by stem cells, have been hypothesized as a treatment for the regeneration of tissue.
This was discovered during investigations in which it was observed that the repairing effect of stem cells can be replicated using only exosomes. This, in turn, opened the door to a method of regenerative medicine therapy that is completely free of stem cells.
The treatment is simple. Immediately upon applying the exosomes directly into a wound or deteriorated tissue, it will improve the communication among affected cells. These exosomes will send proteins which help cells to both regulate themselves and repair tissue.
What Can Exosome Therapy Treat?
As it is capable of regenerating many different types of tissue, exosome therapy is chiefly applied in the treatment of wounds and to diminish the effects of wear and aging on the body. Where treating wounds are concerned, exosome therapy has been proven empirically to produce two effects upon application:
A notable decrease in pain and inflammation: this is the first potential effect. This is due to exosomes being rich in immunomodulatory proteins which both facilitate and regulate the immune response of the human body. This is done through T Cells and NK Cells, which leads to reduced pain and swelling in the affected area.
Repairing and Remodeling of Tissue– the second possible effect is because exosomes have the remarkable ability to instruct other cells around them to repair themselves and surrounding tissue. This brings with it long-lasting regeneration and symptom relief.
How Is This Treatment Applied?
One of the principal application routes is via injection directly into the wounded area– or the area in which one desires treatment. Exosome ampules administered in this form can count on a high concentration of exosomes, along with a smaller concentration of other cellular components like cytokines and chemokines, being delivered into the patient.
This procedure does not require any heavy set-up time, and can be realized in a clinic. Injection can be done with a fine needle to reduce any possibility of pain, and there is no recovery time required after the application.
Who Can Use Exosome Therapy?
This cell-free regenerative medicine treatment can be very beneficial for people suffering from a wide variety of illnesses. Currently, research is being conducted to discover the true reach that this treatment has– but nevertheless, marked improvement has been found in patients suffering from chronic inflammation, immune-system disorders, degenerative diseases and Lyme disease.
The deterioration that the body can suffer as a result of genetics, environmental factors, or caused by chronic diseases can be assuaged upon receiving a high dose of exosomes, which reduce inflammation and spur repairing in the tissues.
Learn More About Treatment With Exosomes
In a matter of years, the number of applications exosomes are being used for has multiplied in several different fields of interest. Currently, it is being studied for its use as a cellular therapy treatment with no cells, as well as in regenerating tissue, diagnostics, and the treatment of cancer, among other promising studies.
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Gordie Howe’s Stem Cell Treatments Support a Growing Appeal for These Therapies Among Athletes and Baby Boomers
In October, 2014, legendary hockey player Gordie Howe, then 86, was on death’s door after suffering a debilitating acute hemorrhagic, left thalamus stroke. Upon returning home from the hospital, Howe needed someone to lift him from his bed to a wheelchair and back. He couldn’t remember the names of his four children, Marty, Mark, Cathy, and Murray, and his condition continued to grow worse in subsequent weeks. According to an article in New York Magazine, when Mark took hid father to get an epidural to relieve his back pain, the attending physician took one look at Gordie and asked Mark if it might be better to just let his father go. On the rare occasion when Gordie did mange to speak, he would tell his children, “Just take me out back and shoot me.”
Howe retired from hockey at age 52, having scored more goals than any other player. But over the past 10 years, his health declined dramatically—heart disease, dementia, and spinal stenosis—despite his family’s and physician’s best efforts to find medical solutions. After his stroke, Keith Olbermann aired a preemptive obituary on ESPN. The family made funeral plans. Murray, his youngest son, wrote a eulogy.
Around Thanksgiving, 2015, Howe’s family learned about an experimental stem cell treatment that could save his life. The plan was to inject up to 100 million neural stem cells into his spinal column in the hopes that the stem cells would migrate to his brain and help his body repair itself. Howe could improve within 24 hours, and receive the treatment anytime—just not in the United States. The procedure wasn’t FDA-approved, and Howe would have to receive the treatment at a clinic in Tijuana.
Howe’s son Murray, a radiologist, looked into the treatment and thought it was promising. The real concern was transporting the immobile Howe to Mexico. Daughter Cathy worried that he might die during the treatment, but Mark responded bluntly: “If he does die, what’s the difference? He’s going to be gone soon no matter what.”
While the family weighed the stem cell treatment idea, Howe was admitted to the hospital with severe dehydration, caused by his unwillingness to swallow. When he returned home, he still had no use of his right side, and the family

Gordie Howe, mid-career
assumed he would never walk again. The Howe children decided to give the stem cell treatments a try.
Two days later, the Howes flew their Dad to San Diego. In the air, Gordie grew agitated and got the attention of a flight attendant, who spent 10 minutes kneeling by his seat trying to understand something he wanted to tell her. Due to his profound memory loss, Howe didn’t know he had suffered a stroke, why he was on a plane, or where he was going. But he remembered one thing, which he managed to whisper to the fight attendant: “I was a pro hockey player.”
The next morning, Marty and Murray drove with their father across the border to Clínica Santa Clarita, where Gordie bent over a table to expose his lower back so that a needle could be inserted into his spinal canal to inject the stem cells. Howe was given two types of stem cells – neural stem cells and mesenchymal stem cells. The second type, derived from bone marrow, has anti-inflammatory properties and secretes chemicals that promote healing.
The procedure then required Howe to lie prone for eight hours. After the eight hours passed, Gordie told Murray he needed to use the bathroom and that he intended to walk there in order to do so. Since the stroke, Gordie had only managed to walk one time—10 steps, with a walker. Murray reminded his Dad that he couldn’t walk.
Howe stood up, and with Murray’s support, walked for the first time in more than a month—to the bathroom. This milestone became an oft-repeated story among the Howe family, and Gordie’s revival became an irresistible story for the sports pages. Back home, Gordie returned to something resembling the normal life of an 86-year-old. He pushed the grocery cart, helped with the dishes, and could go fishing so long as one of his sons reminded him that a tug on the line meant he needed to start reeling. The family released a video of Gordie standing stationary, firing a puck, five-hole, past his 8-year-old great-grandson. Keith Olbermann apologized for his premature obituary.
Howe’s children now had to figure out how to share his apparent recovery—a debate that proved just as contentious as their decision to fly him to Mexico for the treatment in the first place—with the world. Both Marty and Mark had played in the NHL alongside their father, but now Murray, the doctor, was giving interviews in his hospital scrubs, endorsing his father’s place in medical “miracle” history. He began referring to the stem-cell treatment as the “Gordie Howe Protocol,” and said that his Toledo-based hospital was looking into conducting an FDA-approved study of the procedure. In one interview, Murray Howe stated that “stem cells are the most promising thing in medicine since the discovery of antibiotics.”
As the story spread, the medical community started to question just how miraculous Howe’s recovery had been.
“Companies selling these products are preying on desperate and vulnerable people and exploiting their hope, much like snake-oil salesmen have done throughout most of human history,” wrote Judy Illes and Fabio Rossi, stem-cell experts at the University of British Columbia, in the Vancouver Sun. Even advocates pointed out that, though the field holds great promise, no reputable studies have shown that such a procedure should work.
And yet, for the children of ailing parents, such skepticism doesn’t matter. Murray’s response to one skeptic was, “What would you do for your father?”
Gordie Howe’s therapy, would cost an average patient about $30,000.
Athletes, whether playing or retired, have a special need for the regenerative capacity that stem cells are believed to provide. Athletes break bones, strain ligaments, bash knees and wear out cartilage. If stem cells’ restorative capability is proven, they could be considered the latest form of sports medicine.
Since Howe’s treatment in late 2014, two other athletic legends have received stem cell treatments—former quarterbacks Bart Starr and John Brodie. And the rest of the population, particularly aging baby boomers, isn’t far behind.
Still, while accepta

For its part, the FDA is drafting guidelines, although the U.S. and Canada still trail other countries in approving stem cell treatments.
Last year, the FDA issued draft guidelines to clarify what types of human cell therapy it regulates. The short answer: Most of them, with “limited exceptions,” according to an FDA email sent in response to questions from The San Diego Union-Tribune. These exceptions include cells or tissues that are “minimally manipulated,” not given with any other product and perform the same function in the donor as in the recipient.
All other stem cell therapies are seen as involving human cells, tissues and cellular and tissue-based products – also known as HCT/Ps – regulated by the FDA’s Center for Biologics Evaluation and Research.
“We understand that determining the appropriate regulatory path for HCT/Ps can be challenging, and the FDA is working diligently to develop guidance to help sponsors and physicians understand how to apply federal regulations to this complex and emerging field,” the agency said.
In January 2015, University of California, Davis stem cell researcher and blogger Paul Knoepfler estimated that more than 100 unauthorized stem cell clinics were operating in the United States. Later that year, he increased that estimate to up to 200.
Then on May 6, he wrote on his blog: “We are seeing a flood of professional athletes getting stem cell treatments in the past few years.”
Athletes and others who want these treatments bristle at what they call cumbersome, time-consuming regulations in the U.S. The situation can be urgent for seriously ill patients.
While it hasn’t been proven that the stem cells enabled his recovery, by all indications Gordie Howe’s health has improved significantly since receiving stem cell treatments. In November, 2015, Murray Howe said that his father’s physicians in the U.S. recommended hospice care in the weeks after the stroke, and the family was told he wouldn’t last more than two or three weeks,
“Then, suddenly, he is raking and sweeping and goofing around in the back yard,” Murray said.
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Sources: The San Diego Union-Tribune, New York Magazine
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Stem Cell Treatments Normally Used for Cancer Patients are Helping Multiple Sclerosis Patients
The British Broadcasting Corporation (BBC) recently reported that stem cell transplant treatments normally used for cancer patients are helping Multiple Sclerosis (MS) patients in the UK. According to the January 18, 2016 report, 20 patients received bone marrow stem cell transplants using their own stem cells, and that at least some of the patients who were paralyzed by MS are able to walk again post-treatment.
Approximately100,000 people in the United Kingdom suffer from MS, with most new patients diagnosed between the ages of 20 and 30 years of age.
“To have a treatment which can potentially reverse disability is really a major achievement,” says Prof Basil Sharrack, of Sheffield’s Royal Hallamshire Hospital in Sheffield, England.
The treatment, known as autologous hematopoietic stem cell transplantation (HSCT), involves the intravenous infusion of autologous or allogeneic stem cells harvested from the patient’s own bone marrow to reestablish hematopoietic function (formation of blood or blood cells) in patients whose bone marrow or immune system is damaged or defective by chemotherapy. Using stem cells harvested from the patient’s bone marrow helps rebuild the immune system. The theory is that these newly harvested cells are at such an early stage in development that the cellular defects that result in MS do not exist.
“The immune system is being reset or rebooted back to a time point before it caused MS,” says Prof John Snowden, consultant hematologist at Royal Hallamshire Hospital.
The BBC’s Panorama program spoke to several MS patients who have undergone the stem cell transplant.
Steven Storey was diagnosed with MS in 2013 and, within a year, went from being an able-bodied athlete to wheelchair dependent and losing sensation in much of his body.
“I went from running marathons to needing 24-hour acute care. At one point I couldn’t even hold a spoon and feed myself,” Storey says.
Within a few days of the transplant Storey was able to move his toes, and after four months he could stand unaided.
While Storey still needs a wheelchair for mobility, he calls his progress astounding.
“It’s been incredible,” he says. “I was in a dire place, but now I can swim and cycle and I am determined to walk.”
The Royal Hallamshire Hospital along with hospitals in the United States, Sweden and Brazil, is part of an international clinical trial called MIST that is assessing the long-term benefits of the stem cell procedure on MS patients. Study participants all have relapsing remitting MS (RRMS), and received intensive chemotherapy to completely destroy the patients’ immune systems.
Treatment costs are about the same as the annual cost for existing treatments, and the stem cell treatment does not require the use of new or existing medications.
Prof Richard Burt of Northwestern University in Chicago carried out the first hematopoietic stem cell transplantation for MS in 1995, and is coordinating this current MIST international trial, which began in 2006.
“There has been resistance to this in the pharma and academic world,” Burt says. “This is not a technology you can patent and we have achieved this without industry backing.”
A study published last year involving MS patients in Chicago showed significant reductions in neurological disability, and for some the improvements persisted for at least four years, although there was no comparative control group.
The outcomes of the current international trial will be reported in 2018, and may determine whether the stem cell transplant becomes a standard in the United Kingdoms health care system for many MS patients.
“Ongoing research suggests stem cell treatments such as HSCT could offer hope, and it’s clear that in the cases highlighted by Panorama they’ve had a life-changing impact,” says Emma Gray, M.D., head of clinical trials at UK’s MS Society.
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