How Exosome Therapy Differ from Stem Cell Therapy
Exosomes are potent microvesicles released by adult mesenchymal stem cells. They have the ability to help restore cells in the body by improving cell to cell communication.
Exosomes are not cells, and they are smaller than cells. When compared to adult stem cells, exosomes have much more growth factors which give them a better clinical and aesthetic potential than stem cells.
It’s a cell-free cell therapy, this makes it safer compared to other cellular therapy, because there’s no risk of rejection in graft Vs host.
Unlike some other cellular therapies, exosomes do not produce host graft reactions, because they do not carry HLA genetic information and are not cells but extracts of the cells (released by cells).
Exosomes have a superior regenerative capacity, because they are obtained from newborn umbilical cord tissue mesenchymal cells, which means they have not been exposed to any contaminating or toxic agent because our cells are as healthy as our body.
Exosomes improve the signaling between cells, thereby making them useful to revitalize, rejuvenate, restore, and cause anti-inflammatory effects in the body.
When compared to autologous adult stem cells, exosomes have much more healthy growth factors which gives them a better clinical and aesthetic potential than stem cells.
Exosomes are less complicated products to transport because the cells used in cellular therapy must be applied to the patient very quickly because they are live cells. In the laboratory, once they are thawed the doctors have limited time to apply them. However, with exosomes, they last longer, because as they are proteins they do not denature and can last for longer periods.
Exosomes is a superior product to autologous treatments because they do not require a surgical procedure, they come in a vial that can be injected directly, significantly reducing the risk and complications of a surgical procedure.
It is a superior product to autologous stem cell therapy because the patient’s cells have the same age and the same quality. For example, if a patient is a smoker and intoxicated, obviously the health of his cells is not the best. That is why the most indicated product is a donor product that is pure and free of toxins.
Mesenchymal cell-derived exosomes are preferably used in regenerative medicine. These cells are excellent regenerative cells due to their multipotent nature, therefore MSCs derived exosomes are superior to other exosomes products.
The Cellgenic lyophilized exosomes are derived from mesenchymal cells, which makes it superior to other exosome products, because mesenchymal cells have superior and excellent regenerative capacity.
This is why exosome therapy, especially Cellgenic lyophilized exosomes should be a doctor’s first choice.
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Exosome Therapy – The Secret Treatment of Anti-Aging
Overview – The Secret Treatment of Anti-Aging
Over the past few years, exosomes had made a name in the field of rejuvenation and antiaging. Based on the available data, it seems that exosomes will be an integral part of rejuvenation therapy, especially in people interested in stem cell therapy.
Unsurprisingly, many people have never heard of exosomes. So, what exactly are exosomes? How would they help with aging? And what is the difference between exosome therapy and stem cell therapy?
In this article, we will answer all of these questions to help you understand the potential role of this innovative technique.
What are exosomes?
Inside your cells, there are several components that serve different functions. We call them organelles. When these components fuse with the membrane of the cell, exosomes form.
Close inspection of these exosomes shows that they contain protein, lipids, RNA, and other elements of the hosting cell.
Using this complex physiological concept, researchers used stem cell-derived exosomes to repair different tissues. The unique blend of components found inside of these vesicles makes exosomes very effective in boosting the body’s own regenerative ability.
Moreover, exosomes help with getting rid of cytotoxins, making them very effective in dampening chronic inflammation.
How will exosome therapy help your skin
As we age, our skin becomes prone to age-related deterioration, such as wrinkles. Primarily, these issues originate when you can’t regenerate the lost components of your skin.
The good news is that exosomes might just be the solution you’ve been looking for. This treatment will delay the aging process and promote skin regeneration.
When studied in the laboratory, exosomes showed some impressive effects in delaying the onset of skin aging. Researchers found that this therapy boosts the development of fibroblasts, which are a special type of cells that ensure your skin’s structural integrity and elasticity.
Today, the topical use of exosome therapy can be a fantastic way to slow down the dermatological effects of aging.
Perhaps the best thing about exosomes is the fact that there is no risk of rejection since they are not real tissues but rather a trigger for your own tissues to heal themselves.
What is the difference between stem cell therapy and exosomes?
Stem cell therapy revolves around using whole cells to replace lost tissue. Conversely, exosomes are vesicles that detach from the cells. The way that exosomes help with rejuvenation is by helping other cells using the components carried in the vesicles.
Another key difference between stem cells and exosomes is that the former is only obtained from specific areas of the body, such as:
- Bone marrow
- Blood
- Fat tissue
On the other hand, you can get exosomes from all types of cells.
Takeaway message
The use of exosomes in the field of rejuvenation therapy revealed very promising results in preliminary research studies. If used properly, the clinical applications of this technique could be vast, extending beyond esthetic aspects.
We hope that this article helped you appreciate the role of exosome therapy in addressing the aging process.
Learn more about exosome therapy and the possibility to receive it in Cancun, México by clicking on this link.
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Medical applications of exosomes
Medical applications of exosomes
Exosome therapy is gaining popularity in regenerative medicine. So what exactly are exosomes? Exosomes are particles that are released but cannot be replicated. They are intrical in how cells talk to each other. One cell will have a bunch of vesicles that leave and head to another cell to deliver a “message.” These vesicles contain information in the form of chemicals, cytokines to particles of messenger RNA.
Where are Exosomes found?
Exosomes are produced from stem cells and can be found in a variety of tissues.
How are they different from Stem Cells?
Exosomes are contained in stem cells. They are messenger cells that travel to communicate with other cells to produce the needed proteins to repair damaged areas. The use of exosomes does not require donor cells to be injected in the body. Exosomes can be extracted from mesenchymal stem cells (MSCs), sterilized and then injected into the body.
Stem cell therapy injects donor cells into a specific location. These stem cells grow and divide to repair the injured area and create healthier cells overtime. Exosomes are extracted from mesenchymal stem cells and like stem cells are injected into the injured area. Exosomes get to work at communicating with the patient’s own cells and enhance communication among the cells to generate the necessary and needed cells for healing.
What Exactly is Exosome Therapy ?
Exosome products are generally used for orthopedic injuries. Much like stem cell therapy, the exosomes would be injected into the injured site. This is generally an outpatient therapy that is relatively painless.
What does Exosome Therapy Treat? (Medical applications)
Exosome therapy is used for a variety of musculoskeletal injuries, chronic pain, degenerative diseases and genetic disorders. Aging and injuries suppress your cells ability to communicate with each other. The whole purpose of exosomes is to promote communication between cells to repair damaged tissues.
Exosomes are also used to help repair the skin from effects of aging. Overtime, the dermal layer of the skin is damaged because of fragmentation in the collagen, resulting in the signs of aging and hindering the ability to heal wounds. Exosomes have been found to help the body ramp up its collagen production. Exosomes also help inhibit inflammatory cytokines. This means exosomes can help with Atopic Dermatitis, a common skin disorder.
Exosomes can also help with lyme disease. Lyme disease is a very complex disease that compromises the immune system. This can lead to the disruption of cellular health and function. Oftentimes, lyme disease patients experience difficulty with inflammation which exosomes are also known to treat.
Are Exosomes Safer than Stem Cells
While both therapies have a low risk of complications, exosome therapy does not involve a surgical procedure for harvesting cells. Stem cells’ primary job is to grow and divide new and healthy cells from the donor cells. At times these cells may rapidly multiply resulting in a tumor. Exosomes do not multiply, rather they are responsible for improving the communication among cells.
If you want to become a specialist in stem cell therapies, exosomes and MSCs with us, check our next training dates here
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Exosomes: Everything you need to know about this new therapy
Exosomes: everything you need to know about this new therapy
Stem cell-derived exosome therapy is an effective and safe way to relieve chronic pain, leaving behind the need for invasive treatments, such as surgery or drugs with undesirable side effects.
What is exosome therapy?
Normally our cells release substances through envelope-like structures called vesicles. Exosomes are a type of vesicle produced especially by stem cells (mesenchymal cells).
In essence, these small messengers transport crucial molecules or substances, such as signaling proteins or genetic information from one cell to another in order to modulate or generate a response.
The aim of these vesicles is to enhance nerve signaling between cells to reduce the inflammatory response, while at the same time stimulating cell regeneration and modifying immune reactions to pathogens and other diseases.
Why do exosomes relieve pain and inflammation?
With aging, our reparative cells lose some of their ability to respond. Some environmental factors, genetic alterations, or chronic diseases, such as autoimmune disorders and Lyme disease can also interfere with or alter signaling between cells, leaving them unable to mediate inflammation and repair injured tissues.
The main goal of exosome therapy is to modulate both T cells and NK cells in the immune system. Both cells are critical for a balanced immune response, but when that balance is lost for multiple reasons, the result is often an immune imbalance that causes pain and chronic inflammation that is difficult to manage.
These vesicles work by regulating the activity of these cells. For example, when a joint is affected, exosomes are responsible for sending regulatory signals only to the altered cells to restore their normal function.
Therefore, exosomes play a leading role in the regulation and repair of damaged cells and tissues.
What does this new therapy consist of?
The exosomes are administered through an injectable solution that is applied to the affected area. In a single milliliter of solution, there can be between one and 16 billion exosomes. The dosage will depend on the patient’s needs and the therapeutic plan elaborated by the specialist.
Advantages of exosome therapy:
- The entire process occurs on an outpatient basis.
- It is not invasive, nor does it require anesthesia.
- It does not require previous preparations or a long period of inactivity for recovery.
- As it is a substance identical to the biological ones, it does not generate adverse reactions.
However, after treatment, it is necessary to avoid anti-inflammatory drugs, high-impact activities, or cardiovascular exercise for at least the first two weeks.
The results of the therapy depend on the patient’s age, condition, and severity of the condition. As we age our body deteriorates and responds slowly to signals from the cells, therefore in some cases the results are not immediate and several sessions may be necessary to achieve a noticeable improvement.
Where can I receive treatment with exosomes?
Currently, regenerative medicine is already being applied in different parts of the world.
In some places, the intervention and any other regenerative medicine procedure are certainly more cost-effective.
At Cellular Hope Institute we perform exosome and stem cell therapy in Cancun, Mexico. One of the most affordable and cost-effective locations for patients.
Our team will help you with:
- Scheduling therapy dates.
- Booking airline tickets.
- Providing hotel recommendations: many hotels are located next to the hospital.
- Arranging door-to-door transportation during your stay in Cancun, including assistance from and to the airport, hotel, hospital, and anywhere else you would like to go during your stay.
- Accompanying you from and to the hospital and answering any questions along the way.
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What is Exosome Therapy?
What is Exosome Therapy?
Some of the most cutting edge treatments in regenerative medicine today are based on exosome therapy. Studies of this cellular therapy have yielded optimistic prospects, and have shown that exosomes can be used in a wide array of applications and types of treatments.
Being such a new therapy, it is important to know their chief characteristics, how they work, and the functions that they are responsible for, as well as how these details are crucial in treatment with exosomes.
What Are Exosomes?
Exosomes are small extracellular vesicles that are secreted by cells. They are responsible for intercellular communication, where they basically act as messengers carrying valuable protein signals and genetic information (DNA & RNA) between the cells.
They can spread throughout the whole body, delivering messages that tell the cells how to behave, what is happening in the nearby area, or what they should be producing. These messengers are produced by the cells in our own body naturally, and Stem Cells are the chief producers.
What Does Treatment With Exosomes Entail?
Exosomes, being mainly produced by stem cells, have been hypothesized as a treatment for the regeneration of tissue.
This was discovered during investigations in which it was observed that the repairing effect of stem cells can be replicated using only exosomes. This, in turn, opened the door to a method of regenerative medicine therapy that is completely free of stem cells.
The treatment is simple. Immediately upon applying the exosomes directly into a wound or deteriorated tissue, it will improve the communication among affected cells. These exosomes will send proteins which help cells to both regulate themselves and repair tissue.
What Can Exosome Therapy Treat?
As it is capable of regenerating many different types of tissue, exosome therapy is chiefly applied in the treatment of wounds and to diminish the effects of wear and aging on the body. Where treating wounds are concerned, exosome therapy has been proven empirically to produce two effects upon application:
A notable decrease in pain and inflammation: this is the first potential effect. This is due to exosomes being rich in immunomodulatory proteins which both facilitate and regulate the immune response of the human body. This is done through T Cells and NK Cells, which leads to reduced pain and swelling in the affected area.
Repairing and Remodeling of Tissue– the second possible effect is because exosomes have the remarkable ability to instruct other cells around them to repair themselves and surrounding tissue. This brings with it long-lasting regeneration and symptom relief.
How Is This Treatment Applied?
One of the principal application routes is via injection directly into the wounded area– or the area in which one desires treatment. Exosome ampules administered in this form can count on a high concentration of exosomes, along with a smaller concentration of other cellular components like cytokines and chemokines, being delivered into the patient.
This procedure does not require any heavy set-up time, and can be realized in a clinic. Injection can be done with a fine needle to reduce any possibility of pain, and there is no recovery time required after the application.
Who Can Use Exosome Therapy?
This cell-free regenerative medicine treatment can be very beneficial for people suffering from a wide variety of illnesses. Currently, research is being conducted to discover the true reach that this treatment has– but nevertheless, marked improvement has been found in patients suffering from chronic inflammation, immune-system disorders, degenerative diseases and Lyme disease.
The deterioration that the body can suffer as a result of genetics, environmental factors, or caused by chronic diseases can be assuaged upon receiving a high dose of exosomes, which reduce inflammation and spur repairing in the tissues.
Learn More About Treatment With Exosomes
In a matter of years, the number of applications exosomes are being used for has multiplied in several different fields of interest. Currently, it is being studied for its use as a cellular therapy treatment with no cells, as well as in regenerating tissue, diagnostics, and the treatment of cancer, among other promising studies.
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Reasons to Choose Cellular Therapy in Mexico
Reasons to Choose Cellular Therapy in Mexico
Reasons to Choose Cellular Therapy in Mexico
What is Cellular Therapy?
Cellular Therapy, which is also known as regenerative medicine, is a new field of medicine today which aims to promote the repairing of diseased, dysfunctional, or lesioned tissues using Stem Cells and their derivative products.
Stem Cells are a basic building block of the human body– before cells are specialized into becoming lung cells, heart cells, or brain cells, they are stem cells. Under the right conditions in vitro or in a lab, stem cells can multiply to form more cells, which are called daughter cells, which are the ones that become specialized cells in the tissue that is attempting to be treated.
Regenerative medicine helps to stimulate proper healing processes within the body– and although there are other types of regenerative treatments available, there is no question that therapy using Mesenchymal Stem Cells is the most powerful available to physicians today. It has been proven through clinical trials that these cells can be used to treat a wide array of medical conditions, especially in the treatment of musculoskeletal conditions.
It can also largely reduce the long treatment times that are common with the standard of care for lesions and other conditions, as well as reduce rehabilitation time from years to months, providing a valuable alternative for expensive joint surgeries.
Stem Cells also have an incredible capacity to combat illness within the body, fortifying the immune system in patients and lowering inflammation common with autoimmune disorders. Due to the immune booster that cellular therapy can offer, many clinics are offering IV lines available for patients which are looking to use stem cells to stimulate their immune system. This immune system booster can be especially useful for increasing the quality of life and outlook of patients which are immunocompromised.
The Most Important Properties of Stem Cells Are:
Their ability to multiply and regenerative themselves
Their capacity to heal and renew damaged tissues
Cellular Therapy treatments based in Mexico have become a revolutionary modality for medical treatments– this is because of the benefits reported from patients. This can include reduced inflammation, increased mobility, and the healing of scar tissue, among other things. Because of this increase in popularity, many people are looking for cellular therapies that are both quality and affordable.
But, at the same time, you might be wondering– Why Mexico? What are the advantages?
Reasons to Undergo Cellular Therapy in Cancun, Mexico.
Chief among the many advantages that come with receiving your cellular therapy treatment in Mexico, there is the possibility to cultivate and reproduce, in a laboratory environment, those cells which have been extracted from patients. That is to say that a patient can be administered a much larger concentration of cells, which leads to improved results.
Additionally, Mexico is a wonderful option for those treatments that require a more invasive approach– a larger operating team, more medical products and PPE. Mexico is one of the Western Hemisphere’s largest medical tourism capitals, which means that treatments there are performed in hospitals that comply with FDA regulations, and are offered at a more affordable price point.
One can imagine that these types of treatments require a large investment on the side of the patient, however, the cost of a multiple-day cellular therapy treatment in Mexico, is far more affordable than the same treatment– that is, without the ability to use culture-expanded cells, in the United States and Canada.
Because of this, Mexico is one of the best places to administer regenerative medicine therapies, because of its:
- Affordability
- Better Cellular Product — including the ease of cultivating cells in a laboratory, and the ability to use naive cells.
- Legal status of a wide variety of treatments
Cellular Hope Institute
At Cellular Hope Institute, we evaluate, diagnose, and treat patients around the world on a daily basis, with the latest regenerative medicine modalities available today.
We provide each and every one of our patients with an extensive support network to ensure that their experience is completely worry-free. We arrange travel and accompany you every step of the way, to guarantee that your trip to Cancun is calm, safe, and enjoyable.
Cellular Hope Institute
Our Team Will Assist You With:
- Scheduling your treatment dates
- Booking a flight
- Hotel reservations– there are many just a short walk away from the hospital
- Organizing transport during your stay in Cancun, including to and from the airport, hotel, hospital, and any other place you’d like to go during your stay.
- Accompanying you to and from the hospital, and answering any questions you might have along the way.
Additionally, our hospital is located in the center of Cancun, in an area known as ‘Stem Cell Circle’. This area is well known in the city as a collection of clinics and hospitals which treat patients and conduct research in the field of regenerative medicine.
We are committed to inspiring hope and increasing the wellbeing of our patients, while at the same time offering an effective treatment that combines careful screening and a professional atmosphere in which respect for the patient’s health and happiness is placed above all.
Our mission is to offer our patients the best experience possible through the commitment of our full staff, from patient outreach and coordination, to your operating physician. Additionally, we are committed to working towards alleviating your condition, instead of working to target its symptom– bringing the latest technology and quality care to every patient that comes through our door, because they are our top priority.
Our team of highly-qualified experts is always ready to help you at the Cellular Hope Institute.
Get to know the list of conditions that can be treated at our center by visiting the link below;
Additionally, you can contact us directly through the following email address:
info@cellularhopeinstitute.com
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How Exosomes Can Revolutionize Your Healthcare Practice
Cellgenic has worked closely with physicians all around the world for over a decade, and in working shoulder to shoulder with the rest of the medical community, we’ve gotten a feel for what we feel their main grievances are when incorporating regenerative medicine into their practice. We’ve found that primarily, the largest hurdles have been the large upfront costs, the long procedure times, and the difficulty procuring patients.
For a long time, most of the history of the nascent field of regenerative medicine, physicians would have to spend multiple thousands of dollars training themselves to use the procedures required to treat patients. In order to use this training, they would need to buy large, heavy, and expensive medical processing equipment in order to actually process the cellular samples. And after that, they would have to go through the trouble of procuring the enzymes and medical supplies needed to perform the procedure itself.
Every step of the process was mired with difficulty, and all of this was before even the patient acquisition process, which has the potential to completely make or break a practice. This is to not even mention the procedure itself, which can take anywhere from three to five hours of a physician being on their feet, and a patient being subdued under local anesthesia. The final result is an uncomfortable and drawn out procedure that regenerative medicine physicians have been working for years to optimize.
Cellgenic Exosomes is the company’s flagship product, which stands ready to revolutionize the practice of regenerative medicine as we know it today. Exosomes are extracellular vesicles which float freely within the blood, very much like platelets. But that is where the similarities end, because exosomes have been recently discovered to do far more than previously thought. Current science has identified them as one of the cornerstones of intercellular communication, as the enzymes that they secrete are responsible for cell-signalling, including calling healthy cells to begin the process of repairing damaged tissue. Because they consist of proteins, they are able to be administered without a risk of rejection from the patient, and they’re able to immediately get to work within the body, utilizing their growth factors and anti-scarring proteins to target inflammation and damaged tissue within the body.
Utilizing a potent combination of growth factors and anti-scarring proteins, they target inflammation and damage within the cells and tissues of the body and begin repairing it. The administration of Cellgenic Exosomes is simple. Every order arrives cryogenically-preserved under dry ice, and from there physicians can store them in the freezer for over one year. To administer, they simply need to be thawed out and injected into the patient, without the need for expensive and bulky equipment. All in all, this new process should not take more than forty-five minutes, and has lower upfront costs than the previous standard of care for regenerative medicine practitioners.
For more information, please visit https://cellgenic.com/, or contact info@stemcellsgroup.com
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ISSCA Opening of Uccle, Belgium Center with GCell & Stem Cell Training
After several months of organizing and developing a location, the Global Stem Cells Group has finalized the construction of a laboratory and regenerative medicine research center in Uccle, Belgium.
This facility serves both as a regenerative medicine treatment and research center, but also as a plastic surgery clinic. In addition to this, one of the primary goals of the Center is to serve as a place for the fostering of knowledge and experience regarding the different products and equipment required for the application of cellular therapies. As part of the inaugural ceremony a group of physicians were trained in the setup and use of the various regenerative medicine protocols and application process of these cells into the patients.
This center is a push into Europe for the Global Stem Cells Group. As the science advances, newer and more advanced therapies and technologies are being developed and released into the market with each passing month.
With the European Union being one of the largest consumer markets in the world, the finalization of a brick-and-mortar location in Brussels, Belgium is one that will mean great things for the Global Stem Cells Group, and the presence and proliferation of regenerative medicine throughout Europe and the world.
“This was a wonderful opportunity that we could have. It goes to show that even during this pandemic, the medical community is one that is still going strong. We’re still rallying together to look for new breakthroughs, and come up with the most beneficial treatment options for patients,” Said Benito Novas, founder of the International Society for Stem Cell Applications, “In addition to this, it also provides an excellent platform for the distribution of regenerative medicine therapies and equipment, including the revolutionary new GCell Machine,”
Indeed, the inaugural training at the Stem Cell Center in Uccle, Belgium was one that covered both of the more traditional methods of stem cell isolation and application– adipose and bone-marrow derived autologous cells, but this training was also one of the first in which the company had the ability to demonstrate the novel GCell Machine. Using a precise system of blades and filters, it is able to process a stem cell sample from adipose tissue in less than half of the time that it would take a physician to do so through traditional means.
This allows the patient to be more comfortable throughout the shorter procedure, as less anesthesia is also required than when operating under traditional means. The GCell is a minimally invasive, portable machine that allows physicians to fully unlock the potential of regenerative medicine as a component in their practice. Using their global network of distributors and licensed vendors, Global Stem Cells Group is working fervently to ensure no interruption in the global availability of the most cutting-edge regenerative medicine products.
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How Cellgenic MSCs Revolutionize Regenerative Medicine
Stem Cells are revolutionizing the field of regenerative medicine, due to their intelligence. Once administered into the patient, they are able to identify and target areas of disease and damage. Adimarket’s Mesenchymal Stem Cell Product excretes growth factors, cytokines, and proteins, which all play a key role in the regeneration of tissue. Their anti-inflammatory and immunomodulatory properties mean that it is difficult for them to be rejected by the body. Additionally, they increase blood flow to the vital organs which need it the most.
Many proprietors of MSC products will claim that it is not necessarily important to have a high ratio of viable cells. They claim that it does not matter how many cells are ‘not viable’, or dead, so long as there is a high enough number of viable cells– however, current research has shown that this is not the case. These dead cells are detectable by the immune system, and it is believed that they can create an inflammatory response within the body at the treatment area, which would lower the effectiveness of the regenerative medicine treatments.
This bending of the science is harmful to our industry, which is why knowledgeable purveyors put one thing above all else– consistency. Our cellular concentrations are the same throughout each batch, and we make sure that there is a high ratio of viable cells. All of our samples are independently verified by a third party laboratory, and have been selected for their phenotypic and genotypic profile, characterized for optimum growth and stability. When the proper care is taken, Mesenchymal Stem Cell products have been identified as having the highest output of growth factors and stem cell factors among the current standards of care– as well as properties of angiogenesis, immunomodulation, and the potential for endogenous repair.
Cellgenic has been working for over a decade, constantly reinventing itself and reinforcing the products that we offer with the latest advancements in the field of regenerative medicine. We take every painstaking measure possible to ensure that the cellular samples that our customers use to treat their patients are second to none– this includes the consistent concentrations of our sample, which are the same throughout ensuring that every patient gets the same treatment. We offer the product in 10 million or 30 million live total nucleated cells, where other fabricators would have the same number of total cells. We ensure that every single product that we send out has been tested for low amounts of annexin, which is a cellular protein which serves as a marker for cell death.
All our Mesenchymal Stem Cell products come in 1cc vials cryogenically preserved– they are shipped overnight within the United States, conveniently delivered to your door in the morning. For use, the product is passively thawed between the palms of your hands– and ready to use when your patients are. MSC 10 contains 10 million live cells and is recommended for a single joint, or a small area. However, the MSC pure pro has 30 million live cells,and can be used for larger applications, or for up to three joints in the same patient at the same time.
If you are interested in finding out more about Cellgenic MSCs, you can send an eMail to info@stemcellsgroup.com
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What is Exosome therapy?
Exosomes are extracellular vesicles (that’s particles that release naturally from a cell that cannot replicate) that are responsible for certain genetic information, otherwise known as Exosomes cell to cell communication. They transport molecules that are essential regulators of intracellular information between close and distant cells.
Exosomes play a vital role in the communication and rejuvenation of all the cells in our body. Despite not being a cell, Exosome has proven to be quite important in maintaining a healthy cellular terrain.
Exosomes are typically made by growing stem cells in culture. Taking the media where they grow and then getting rid of the stem cells. Due to the small size of Exosomes, the media is then ultra-centrifuged to concentrate the exosomes.
Exosomes contain different molecular constituents of their cell origin; these include proteins and RNA. Meanwhile, the Exosomal proteins composition varies with the cell and tissue of the origin; most Exsomes contains an evolutionarily conserved common set of protein molecules.
HOW TO ISOLATE EXOSOME FROM CULTURE STEM?
Exosomes can be isolated from culture stem cell using the method Ultracentrifugation. Often combined with sucrose density gradients, they float the relatively low-density Exosomes from other microvesicles. Cells and larger particles are removed by sequentially increasing the centrifugal forces. These procedures can take up to 30hours and requires an ultracentrifuge, extensive training and specialized equipment.
This method provides highly enriched exosomes but requires specialized training and equipment.
Now, this is how Exosomes works:
Exosomes carry genetic information. Protein and messenger RNA, they can relay this information, letting cells know when to and how to react. This Exosomes cell-to-cell communication is possible due to its unique shape and content.
Exosomes from young stem cells rejuvenate the older cells and assist in calming an overreactive immune system or modulating it to respond in a coordinated and more effective fashion.
WHAT IS EXOSOME THERAPY?
Exosome therapy is one of the hottest areas of regenerative medicine treatment. Researchers have given us valuable insight into the practical functionality of exosomes. While stem cells are usually responsible for the rejuvenation of older cells, they may not be able to supply all the information needed. So supporting Exosome function could have a greater positive effect, by providing a new piece of information to enhance the healing process.
Exosome therapy is a minimally invasive procedure commonly used in orthopedic injuries, for anti-aging and some other degenerative diseases. Exosomes treatment contains growth factors, messenger RNA, micro RNA, cytokines and other biologically active molecules in conjunction with stem cell therapy to speed up healing benefit.
Exosome therapy can be injected into the affected area like in orthopedic injuries or given intravenously for anti-aging.
This Exosome injection is administered directly into the affected area, and the dosing for every patient varies, and there is no set protocol.
Exosomes treatment is gaining popularity recently, due to its ability to transfer molecules from one cell to another via membrane vesicle, therefore influencing the immune system, such as dendrite cells and B cells.
What is exosome therapy used for?
HAIR LOSS: Exosomes injection can be used to regrow hair loss due to its growth factor content. When injected, Exosome will trigger healing, cell stimulation and natural regeneration of these hair follicles. Exosome hair loss therapy is cutting-edge in hair restoration. According to research, there is a positive relationship between Exosomes and Hair loss. Exosomes are ideal for people with thinning hair, excessive shedding or hair loss proper. This is because Exosomes are regenerative cells that can heal, repair, stimulate and restore cells and tissues.
LYME DISEASE: Exosomes may help to regulate processes in the body, and may also be beneficial to patients with Lyme disease. Lyme disease is a very complex disease, which compromises the immune system. Many Lyme patients suffer from dysfunction of the mast cells, increasing their inflammatory response and metabolic function. Incorporating Exosomes treatment in their treatment regimen may help break the inflammatory response and provide the body with necessary cellular information to facilitate healing.
ARTHRITIS: Arthritis as we all know, is the joint inflammation resulting from an autoimmune disease. Although various types of treatment are available to alleviate symptoms, no known therapy has been confirmed effective in reversing the disease progression.
In the field of regenerative medicine today, with the discovery of extracellular microvesicles, especially exosomes, many researchers have been able to offer a more exciting alternative on this subject matter. Exosome arthritis therapy is believed to play a more substantial role in bone and cartilage remodeling.
In a nutshell, Exosomes provides enormous potential in the field of regenerative medicine. You can advance your understanding of Exosomes and its relationship with stem cell in this course. This is an online-course https://www.cellulartherapycourse.com/ where physicians and medical personnel can get insight and deep understanding of this novel science (Exosome).
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